CTCF in parvalbumin-expressing neurons regulates motor, anxiety and social behavior and neuronal identity

CTCF in parvalbumin-expressing neurons regulates motor, anxiety and social behavior and neuronal identity

Abstract CCCTC-binding factor (CTCF) is a regulator of chromatin organization and has direct effects on gene transcription. Mutations in CTCF have been identified in individuals with neurodevelopmental conditions. There are wide range of behaviors associated with these mutations, including intellect...

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Bibliographic Details
Main Authors: Liron Davis, Prudhvi Raj Rayi, Dmitriy Getselter, Hanoch Kaphzan, Evan Elliott
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Molecular Brain
Subjects:
CTCF
Anxiety
Autism
Neurodevelopment
Parvalbumin
Inhibitory neuron
Online Access:https://doi.org/10.1186/s13041-022-00916-9

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