CFTR dysfunction leads to defective bacterial eradication on cystic fibrosis airways

CFTR dysfunction leads to defective bacterial eradication on cystic fibrosis airways

Dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel by genetic mutations causes the inherited disease cystic fibrosis (CF). CF lung disease that involves multiple disorders of epithelial function likely results from loss of CFTR function as an anion channel co...

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Bibliographic Details
Main Authors: Min Wu, Jeng-Haur Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Physiology
Subjects:
cystic fibrosis
CFTR
bacterial infection
airway epithelia
mucus
bicarbonate
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2024.1385661/full

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