Audiovisual spatial recalibration but not integration is shaped by early sensory experience
Summary: To clarify the role of sensory experience during early development for adult multisensory learning capabilities, we probed audiovisual spatial processing in human individuals who had been born blind because of dense congenital cataracts (CCs) and who subsequently had received cataract remov...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-06-01
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| Series: | iScience |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004222007106 |
| _version_ | 1818253915088486400 |
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| author | Patrick Bruns Lux Li Maria J.S. Guerreiro Idris Shareef Siddhart S. Rajendran Kabilan Pitchaimuthu Ramesh Kekunnaya Brigitte Röder |
| author_facet | Patrick Bruns Lux Li Maria J.S. Guerreiro Idris Shareef Siddhart S. Rajendran Kabilan Pitchaimuthu Ramesh Kekunnaya Brigitte Röder |
| author_sort | Patrick Bruns |
| collection | DOAJ |
| description | Summary: To clarify the role of sensory experience during early development for adult multisensory learning capabilities, we probed audiovisual spatial processing in human individuals who had been born blind because of dense congenital cataracts (CCs) and who subsequently had received cataract removal surgery, some not before adolescence or adulthood. Their ability to integrate audio-visual input and to recalibrate multisensory spatial representations was compared to normally sighted control participants and individuals with a history of developmental (later onset) cataracts. Results in CC individuals revealed both normal multisensory integration in audiovisual trials (ventriloquism effect) and normal recalibration of unimodal auditory localization following audiovisual discrepant exposure (ventriloquism aftereffect) as observed in the control groups. In addition, only the CC group recalibrated unimodal visual localization after audiovisual exposure. Thus, in parallel to typical multisensory integration and learning, atypical crossmodal mechanisms coexisted in CC individuals, suggesting that multisensory recalibration capabilities are defined during a sensitive period in development. |
| first_indexed | 2024-12-12T16:47:39Z |
| format | Article |
| id | doaj.art-72340b6cf06e43e78b8640c1a7098d0d |
| institution | Directory Open Access Journal |
| issn | 2589-0042 |
| language | English |
| last_indexed | 2024-12-12T16:47:39Z |
| publishDate | 2022-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj.art-72340b6cf06e43e78b8640c1a7098d0d2022-12-22T00:18:26ZengElsevieriScience2589-00422022-06-01256104439Audiovisual spatial recalibration but not integration is shaped by early sensory experiencePatrick Bruns0Lux Li1Maria J.S. Guerreiro2Idris Shareef3Siddhart S. Rajendran4Kabilan Pitchaimuthu5Ramesh Kekunnaya6Brigitte Röder7Biological Psychology and Neuropsychology, University of Hamburg, 20146 Hamburg, Germany; Corresponding authorBiological Psychology and Neuropsychology, University of Hamburg, 20146 Hamburg, Germany; Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, ON N6G 2M1, CanadaBiological Psychology and Neuropsychology, University of Hamburg, 20146 Hamburg, Germany; Biological Psychology, Department of Psychology, School of Medicine and Health Sciences, University of Oldenburg, 26111 Oldenburg, GermanyJasti V Ramanamma Children’s Eye Care Centre, LV Prasad Eye Institute, Hyderabad, Telangana 500034, IndiaBiological Psychology and Neuropsychology, University of Hamburg, 20146 Hamburg, Germany; Jasti V Ramanamma Children’s Eye Care Centre, LV Prasad Eye Institute, Hyderabad, Telangana 500034, IndiaBiological Psychology and Neuropsychology, University of Hamburg, 20146 Hamburg, Germany; Jasti V Ramanamma Children’s Eye Care Centre, LV Prasad Eye Institute, Hyderabad, Telangana 500034, IndiaJasti V Ramanamma Children’s Eye Care Centre, LV Prasad Eye Institute, Hyderabad, Telangana 500034, IndiaBiological Psychology and Neuropsychology, University of Hamburg, 20146 Hamburg, GermanySummary: To clarify the role of sensory experience during early development for adult multisensory learning capabilities, we probed audiovisual spatial processing in human individuals who had been born blind because of dense congenital cataracts (CCs) and who subsequently had received cataract removal surgery, some not before adolescence or adulthood. Their ability to integrate audio-visual input and to recalibrate multisensory spatial representations was compared to normally sighted control participants and individuals with a history of developmental (later onset) cataracts. Results in CC individuals revealed both normal multisensory integration in audiovisual trials (ventriloquism effect) and normal recalibration of unimodal auditory localization following audiovisual discrepant exposure (ventriloquism aftereffect) as observed in the control groups. In addition, only the CC group recalibrated unimodal visual localization after audiovisual exposure. Thus, in parallel to typical multisensory integration and learning, atypical crossmodal mechanisms coexisted in CC individuals, suggesting that multisensory recalibration capabilities are defined during a sensitive period in development.http://www.sciencedirect.com/science/article/pii/S2589004222007106OphthalmologyDevelopmental neuroscienceSensory neuroscienceCognitive neuroscience |
| spellingShingle | Patrick Bruns Lux Li Maria J.S. Guerreiro Idris Shareef Siddhart S. Rajendran Kabilan Pitchaimuthu Ramesh Kekunnaya Brigitte Röder Audiovisual spatial recalibration but not integration is shaped by early sensory experience iScience Ophthalmology Developmental neuroscience Sensory neuroscience Cognitive neuroscience |
| title | Audiovisual spatial recalibration but not integration is shaped by early sensory experience |
| title_full | Audiovisual spatial recalibration but not integration is shaped by early sensory experience |
| title_fullStr | Audiovisual spatial recalibration but not integration is shaped by early sensory experience |
| title_full_unstemmed | Audiovisual spatial recalibration but not integration is shaped by early sensory experience |
| title_short | Audiovisual spatial recalibration but not integration is shaped by early sensory experience |
| title_sort | audiovisual spatial recalibration but not integration is shaped by early sensory experience |
| topic | Ophthalmology Developmental neuroscience Sensory neuroscience Cognitive neuroscience |
| url | http://www.sciencedirect.com/science/article/pii/S2589004222007106 |
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