Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)
Serjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosi...
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| Format: | Article |
| Language: | English |
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Universidade de São Paulo
2013-12-01
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| Series: | Brazilian Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400017&lng=en&tlng=en |
| _version_ | 1811333759685885952 |
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| author | Claudia Andréa Lima Cardoso Roberta Gomes Coelho Neli Kika Honda Arnildo Pott Fernando Rogério Pavan Clarice Queico Fujimura Leite |
| author_facet | Claudia Andréa Lima Cardoso Roberta Gomes Coelho Neli Kika Honda Arnildo Pott Fernando Rogério Pavan Clarice Queico Fujimura Leite |
| author_sort | Claudia Andréa Lima Cardoso |
| collection | DOAJ |
| description | Serjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin, kaempferol aglycone and five glycoside derivates were isolated: kaempferol-3-O-α-L-rhamnopyranoside, kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside from the roots and kaempferol, kaempferol 3,7-di-O-α-L-rhamnopyranoside, vitexin, isovitexin and (-)-epicatechin in the leaves. This is the first chemical study reported in the literature about this specie. |
| first_indexed | 2024-04-13T16:57:46Z |
| format | Article |
| id | doaj.art-723438d4227d4cfbbde9b57ae2faa4a8 |
| institution | Directory Open Access Journal |
| issn | 2175-9790 |
| language | English |
| last_indexed | 2024-04-13T16:57:46Z |
| publishDate | 2013-12-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Brazilian Journal of Pharmaceutical Sciences |
| spelling | doaj.art-723438d4227d4cfbbde9b57ae2faa4a82022-12-22T02:38:45ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902013-12-0149477578210.1590/S1984-82502013000400017S1984-82502013000400017Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae)Claudia Andréa Lima Cardoso0Roberta Gomes Coelho1Neli Kika Honda2Arnildo Pott3Fernando Rogério Pavan4Clarice Queico Fujimura Leite5Universidade Estadual de Mato Grosso do SulUniversidade Federal de Mato Grosso do SulUniversidade Federal de Mato Grosso do SulUniversidade Federal de Mato Grosso do SulUniversidade Estadual PaulistaUniversidade Estadual PaulistaSerjania erecta Radlk.(Sapindaceae) is a medicinal plant traditionally used in Brazil. We assayed the ethanolic extract of leaves and roots against seven microorganisms. The REMA (Resazurin Microtiter Assay) assay was used to measure the biological activity in vitro against Mycobacterium tuberculosis and our results showed moderate activity of the ethanolic extract. On the other hand S. aureus, P. aeruginosa, S. setubal, C. albicans, S. cerevisiae and E. coli revealed that the leaves and roots of S. erecta inhibited the growth of all microorganisms. The ethanolic extracts of leaves and roots showed low values of antioxidant activities. The ethanolic extracts of leaves and roots were analyzed by chromatographic and spectrometric methods. (-)-Epicatechin, kaempferol aglycone and five glycoside derivates were isolated: kaempferol-3-O-α-L-rhamnopyranoside, kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside from the roots and kaempferol, kaempferol 3,7-di-O-α-L-rhamnopyranoside, vitexin, isovitexin and (-)-epicatechin in the leaves. This is the first chemical study reported in the literature about this specie.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400017&lng=en&tlng=enSerjania erecta RadlkSerjania erecta RadlkSerjania erecta RadlkSerjania erecta RadlkSerjania erecta RadlkSapindaceaeCipó-cinco-folhasFlavonóidesPlantas medicinais |
| spellingShingle | Claudia Andréa Lima Cardoso Roberta Gomes Coelho Neli Kika Honda Arnildo Pott Fernando Rogério Pavan Clarice Queico Fujimura Leite Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) Brazilian Journal of Pharmaceutical Sciences Serjania erecta Radlk Serjania erecta Radlk Serjania erecta Radlk Serjania erecta Radlk Serjania erecta Radlk Sapindaceae Cipó-cinco-folhas Flavonóides Plantas medicinais |
| title | Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
| title_full | Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
| title_fullStr | Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
| title_full_unstemmed | Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
| title_short | Phenolic compounds and antioxidant, antimicrobial and antimycobacterial activities of Serjania erecta Radlk. (Sapindaceae) |
| title_sort | phenolic compounds and antioxidant antimicrobial and antimycobacterial activities of serjania erecta radlk sapindaceae |
| topic | Serjania erecta Radlk Serjania erecta Radlk Serjania erecta Radlk Serjania erecta Radlk Serjania erecta Radlk Sapindaceae Cipó-cinco-folhas Flavonóides Plantas medicinais |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400017&lng=en&tlng=en |
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