Integrative analysis of purine metabolites and gut microbiota in patients with neuromyelitis optica spectrum disorders after mycophenolate mofetil treatment

Integrative analysis of purine metabolites and gut microbiota in patients with neuromyelitis optica spectrum disorders after mycophenolate mofetil treatment

Abstract Background Neuromyelitis optica spectrum disorder (NMOSD) is a recurring inflammatory demyelinating disease that is commonly observed in Asian countries like China. Prior investigations have shown that mycophenolate mofetil (MMF) with better biocompatibility compared to azathioprine (AZA),...

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Bibliographic Details
Main Authors: Gong Li, Xiaoyu Ma, Lijuan Xia, Ran Wei, Xiran Wang, Cang Li, Yuge Wang, Limin He, Hao Ren, Jian Sun, Wei Qiu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Neurology
Subjects:
Neuromyelitis Optica Spectrum Disorders
Mycophenolate Mofetil
Gut Microbiota
Therapeutic Efficacy
PSP Metabolites
Online Access:https://doi.org/10.1186/s12883-023-03500-3

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