Advanced or metastatic biliary tract cancer in Japan: a study using the Japan Medical Data Center payer claims database
Aim: Biliary tract cancers are aggressive, with poor prognosis. This study describes clinical characteristics, treatment patterns and healthcare resource utilization in patients with metastatic biliary tract cancer in Japan. Materials & methods: This cohort-based study collected data from the...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Becaris Publishing Limited
2023-05-01
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| Series: | Journal of Comparative Effectiveness Research |
| Subjects: |
| _version_ | 1797688162833661952 |
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| author | Ramzi Argoubi Emily S Reese Martina Furegato Patricia Medina Sarah Bobiak |
| author_facet | Ramzi Argoubi Emily S Reese Martina Furegato Patricia Medina Sarah Bobiak |
| author_sort | Ramzi Argoubi |
| collection | DOAJ |
| description | Aim: Biliary tract cancers are aggressive, with poor prognosis. This study describes clinical characteristics,
treatment patterns and healthcare resource utilization in patients with metastatic biliary tract cancer in
Japan. Materials & methods: This cohort-based study collected data from the Japan Medical Data Center
claims database (2014–2018). Results: A total of 325 patients were included; 65.2% were male and the
mean age was 59.2 years. A 47.6% had an Elixhauser Comorbidity Index score ≥5. Most frequent regimens
were gemcitabine + cisplatin (52.9%) for first-line therapy and tegafur + gimeracil + oteracil for secondline
therapy (48.6%) and third-line therapy (27.2%). Approximately 77% of patients had ≥1 hospital
admission, with a median length of 57 days. Conclusion: This study provides insights on the characteristics
and burden of metastatic biliary tract cancer in Japan, highlighting high disease burden in a younger
population. |
| first_indexed | 2024-03-12T01:27:17Z |
| format | Article |
| id | doaj.art-72350535208842c1bb77a86f299d44f5 |
| institution | Directory Open Access Journal |
| issn | 2042-6313 |
| language | English |
| last_indexed | 2024-03-12T01:27:17Z |
| publishDate | 2023-05-01 |
| publisher | Becaris Publishing Limited |
| record_format | Article |
| series | Journal of Comparative Effectiveness Research |
| spelling | doaj.art-72350535208842c1bb77a86f299d44f52023-09-12T13:30:56ZengBecaris Publishing LimitedJournal of Comparative Effectiveness Research2042-63132023-05-0112610.57264/cer-2022-0201Advanced or metastatic biliary tract cancer in Japan: a study using the Japan Medical Data Center payer claims databaseRamzi Argoubi0https://orcid.org/0000-0002-3171-0078Emily S Reese1https://orcid.org/0000-0001-9729-1665Martina Furegato2https://orcid.org/0000-0003-2168-8396Patricia Medina3Sarah Bobiak4Cerner Enviza, Kansas City, MO 64117, USAEMD Serono Research & Development Institute, Inc, Billerica, MA 01821, USA, an affiliate of Merck KGaACerner Enviza, Kansas City, MO 64117, USACerner Enviza, Kansas City, MO 64117, USAEMD Serono Research & Development Institute, Inc, Billerica, MA 01821, USA, an affiliate of Merck KGaAAim: Biliary tract cancers are aggressive, with poor prognosis. This study describes clinical characteristics, treatment patterns and healthcare resource utilization in patients with metastatic biliary tract cancer in Japan. Materials & methods: This cohort-based study collected data from the Japan Medical Data Center claims database (2014–2018). Results: A total of 325 patients were included; 65.2% were male and the mean age was 59.2 years. A 47.6% had an Elixhauser Comorbidity Index score ≥5. Most frequent regimens were gemcitabine + cisplatin (52.9%) for first-line therapy and tegafur + gimeracil + oteracil for secondline therapy (48.6%) and third-line therapy (27.2%). Approximately 77% of patients had ≥1 hospital admission, with a median length of 57 days. Conclusion: This study provides insights on the characteristics and burden of metastatic biliary tract cancer in Japan, highlighting high disease burden in a younger population.biliary tract cancerbiliary tract carcinomacomparative–effectiveness researcheconomic burdenhealth services researchobservational researchoncologyreal-world evidencetreatment patterns |
| spellingShingle | Ramzi Argoubi Emily S Reese Martina Furegato Patricia Medina Sarah Bobiak Advanced or metastatic biliary tract cancer in Japan: a study using the Japan Medical Data Center payer claims database Journal of Comparative Effectiveness Research biliary tract cancer biliary tract carcinoma comparative–effectiveness research economic burden health services research observational research oncology real-world evidence treatment patterns |
| title | Advanced or metastatic biliary tract cancer in Japan: a study using the Japan Medical Data Center payer claims database |
| title_full | Advanced or metastatic biliary tract cancer in Japan: a study using the Japan Medical Data Center payer claims database |
| title_fullStr | Advanced or metastatic biliary tract cancer in Japan: a study using the Japan Medical Data Center payer claims database |
| title_full_unstemmed | Advanced or metastatic biliary tract cancer in Japan: a study using the Japan Medical Data Center payer claims database |
| title_short | Advanced or metastatic biliary tract cancer in Japan: a study using the Japan Medical Data Center payer claims database |
| title_sort | advanced or metastatic biliary tract cancer in japan a study using the japan medical data center payer claims database |
| topic | biliary tract cancer biliary tract carcinoma comparative–effectiveness research economic burden health services research observational research oncology real-world evidence treatment patterns |
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