Calix[4]arene Derivative for Iodine Capture and Effect on Leaching of Iodine through Packaging
A hydrophobic calix[4]arene derivative was investigated for its iodine (I<sub>2</sub>) capture efficiency from gaseous and liquid phase. The iodine uptake was followed by UV-vis spectroscopy. Additionally, the influence of the calix[4]arene derivative–polyolefin system on the leaching of...
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| Format: | Article |
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MDPI AG
2023-02-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/4/1869 |
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| author | Loredana Ferreri Marco Rapisarda Melania Leanza Cristina Munzone Nicola D’Antona Grazia Maria Letizia Consoli Paola Rizzarelli Emanuela Teresa Agata Spina |
| author_facet | Loredana Ferreri Marco Rapisarda Melania Leanza Cristina Munzone Nicola D’Antona Grazia Maria Letizia Consoli Paola Rizzarelli Emanuela Teresa Agata Spina |
| author_sort | Loredana Ferreri |
| collection | DOAJ |
| description | A hydrophobic calix[4]arene derivative was investigated for its iodine (I<sub>2</sub>) capture efficiency from gaseous and liquid phase. The iodine uptake was followed by UV-vis spectroscopy. Additionally, the influence of the calix[4]arene derivative–polyolefin system on the leaching of iodine through packaging from a povidone-iodine-based (PVP-I) formulation was evaluated. In fact, iodine is a low-cost, multi-target, and broad-spectrum antiseptic. However, it is volatile, and the extended storage of I<sub>2</sub>-based formulations is challenging in plastic packaging. Here, we investigated the possibility of reducing the loss of I<sub>2</sub> from an iodophor formulation by incorporating 4-<i>tert</i>-butylcalix [4]arene-tetraacetic acid tetraethyl ester (CX) and its iodine complex in high-density polyethylene (HDPE) or polypropylene (PP) via a swelling procedure. Surface and bulk changes were monitored by contact angle, thermogravimetric analysis (TGA), and UV-vis diffuse reflectance spectra. The barrier effect of the different polymeric systems (embedded with CX, iodine-CX complex, or I2) was evaluated by monitoring the I2 retention in a buffered PVP-I solution by UV-vis spectroscopy. Overall, experimental data showed the capability of the calix[4]arene derivative to complex iodine in solution and the solid state and a significant reduction in the iodine leaching by the PP-CX systems. |
| first_indexed | 2024-03-11T08:21:04Z |
| format | Article |
| id | doaj.art-72355aacfaa2472f847323658e1562bc |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T08:21:04Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-72355aacfaa2472f847323658e1562bc2023-11-16T22:24:23ZengMDPI AGMolecules1420-30492023-02-01284186910.3390/molecules28041869Calix[4]arene Derivative for Iodine Capture and Effect on Leaching of Iodine through PackagingLoredana Ferreri0Marco Rapisarda1Melania Leanza2Cristina Munzone3Nicola D’Antona4Grazia Maria Letizia Consoli5Paola Rizzarelli6Emanuela Teresa Agata Spina7Institute of Biomolecular Chemistry, CNR, Via Paolo Gaifami 18, 95126 Catania, ItalyInstitute for Polymers, Composites and Biomaterials, CNR, Via Paolo Gaifami 18, 95126 Catania, ItalyInstitute for Polymers, Composites and Biomaterials, CNR, Via Paolo Gaifami 18, 95126 Catania, ItalyDepartment of Chemistry, University of Catania, Viale A. Doria 6, 95125 Catania, ItalyInstitute of Biomolecular Chemistry, CNR, Via Paolo Gaifami 18, 95126 Catania, ItalyInstitute of Biomolecular Chemistry, CNR, Via Paolo Gaifami 18, 95126 Catania, ItalyInstitute for Polymers, Composites and Biomaterials, CNR, Via Paolo Gaifami 18, 95126 Catania, ItalyInstitute for Polymers, Composites and Biomaterials, CNR, Via Paolo Gaifami 18, 95126 Catania, ItalyA hydrophobic calix[4]arene derivative was investigated for its iodine (I<sub>2</sub>) capture efficiency from gaseous and liquid phase. The iodine uptake was followed by UV-vis spectroscopy. Additionally, the influence of the calix[4]arene derivative–polyolefin system on the leaching of iodine through packaging from a povidone-iodine-based (PVP-I) formulation was evaluated. In fact, iodine is a low-cost, multi-target, and broad-spectrum antiseptic. However, it is volatile, and the extended storage of I<sub>2</sub>-based formulations is challenging in plastic packaging. Here, we investigated the possibility of reducing the loss of I<sub>2</sub> from an iodophor formulation by incorporating 4-<i>tert</i>-butylcalix [4]arene-tetraacetic acid tetraethyl ester (CX) and its iodine complex in high-density polyethylene (HDPE) or polypropylene (PP) via a swelling procedure. Surface and bulk changes were monitored by contact angle, thermogravimetric analysis (TGA), and UV-vis diffuse reflectance spectra. The barrier effect of the different polymeric systems (embedded with CX, iodine-CX complex, or I2) was evaluated by monitoring the I2 retention in a buffered PVP-I solution by UV-vis spectroscopy. Overall, experimental data showed the capability of the calix[4]arene derivative to complex iodine in solution and the solid state and a significant reduction in the iodine leaching by the PP-CX systems.https://www.mdpi.com/1420-3049/28/4/1869iodine capturecalix[4]arenepovidone-iodinepolyethylenepolypropyleneiodophore |
| spellingShingle | Loredana Ferreri Marco Rapisarda Melania Leanza Cristina Munzone Nicola D’Antona Grazia Maria Letizia Consoli Paola Rizzarelli Emanuela Teresa Agata Spina Calix[4]arene Derivative for Iodine Capture and Effect on Leaching of Iodine through Packaging Molecules iodine capture calix[4]arene povidone-iodine polyethylene polypropylene iodophore |
| title | Calix[4]arene Derivative for Iodine Capture and Effect on Leaching of Iodine through Packaging |
| title_full | Calix[4]arene Derivative for Iodine Capture and Effect on Leaching of Iodine through Packaging |
| title_fullStr | Calix[4]arene Derivative for Iodine Capture and Effect on Leaching of Iodine through Packaging |
| title_full_unstemmed | Calix[4]arene Derivative for Iodine Capture and Effect on Leaching of Iodine through Packaging |
| title_short | Calix[4]arene Derivative for Iodine Capture and Effect on Leaching of Iodine through Packaging |
| title_sort | calix 4 arene derivative for iodine capture and effect on leaching of iodine through packaging |
| topic | iodine capture calix[4]arene povidone-iodine polyethylene polypropylene iodophore |
| url | https://www.mdpi.com/1420-3049/28/4/1869 |
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