Image preprocessing‐based ensemble deep learning classification of diabetic retinopathy

Abstract Diabetic retinopathy (DR) can cause irreversible eye damage, even blindness. The prognosis improves with early diagnosis. According to the International Classification of Diabetic Retinopathy Severity Scale (ICDRSS), DR has five stages. Modern, cost‐effective techniques for automatic DR scr...

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Main Authors: Peter Macsik, Jarmila Pavlovicova, Slavomir Kajan, Jozef Goga, Veronika Kurilova
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:IET Image Processing
Subjects:
Online Access:https://doi.org/10.1049/ipr2.12987
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author Peter Macsik
Jarmila Pavlovicova
Slavomir Kajan
Jozef Goga
Veronika Kurilova
author_facet Peter Macsik
Jarmila Pavlovicova
Slavomir Kajan
Jozef Goga
Veronika Kurilova
author_sort Peter Macsik
collection DOAJ
description Abstract Diabetic retinopathy (DR) can cause irreversible eye damage, even blindness. The prognosis improves with early diagnosis. According to the International Classification of Diabetic Retinopathy Severity Scale (ICDRSS), DR has five stages. Modern, cost‐effective techniques for automatic DR screening and staging of fundus images are based on deep learning (DL). To obtain higher classification accuracy, the combination of several diverse individual DL models into one ensemble could be used. A new approach to model diversity in an ensemble is proposed by manipulating the training input data involving original and four variants of preprocessed image datasets. There are publicly available datasets with labels for all five stages, but some contain poor‐quality images. In contrast, this algorithm was trained on images from a six‐class DDR dataset, including the class of poor‐quality ungradable images, to enhance the classification performance. The solution was evaluated on the APTOS dataset, containing only ICDRSS classes. Classification results of the ensemble model were presented on two different ensemble convolutional neural network (CNN) models, based on Xception and EfficientNetB4 architectures using two fusion approaches. Our proposed ensemble models outperformed all other single deep learning architectures regarding overall accuracy and Cohen's Kappa, with the best results using the EfficientNetB4 architecture.
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spelling doaj.art-723bf6c9b0934e4fb53de857d5620ac82024-02-14T07:53:25ZengWileyIET Image Processing1751-96591751-96672024-02-0118380782810.1049/ipr2.12987Image preprocessing‐based ensemble deep learning classification of diabetic retinopathyPeter Macsik0Jarmila Pavlovicova1Slavomir Kajan2Jozef Goga3Veronika Kurilova4Faculty of Electrical Engineering and Information Technology Slovak University of Technology Bratislava SlovakiaFaculty of Electrical Engineering and Information Technology Slovak University of Technology Bratislava SlovakiaFaculty of Electrical Engineering and Information Technology Slovak University of Technology Bratislava SlovakiaFaculty of Electrical Engineering and Information Technology Slovak University of Technology Bratislava SlovakiaFaculty of Electrical Engineering and Information Technology Slovak University of Technology Bratislava SlovakiaAbstract Diabetic retinopathy (DR) can cause irreversible eye damage, even blindness. The prognosis improves with early diagnosis. According to the International Classification of Diabetic Retinopathy Severity Scale (ICDRSS), DR has five stages. Modern, cost‐effective techniques for automatic DR screening and staging of fundus images are based on deep learning (DL). To obtain higher classification accuracy, the combination of several diverse individual DL models into one ensemble could be used. A new approach to model diversity in an ensemble is proposed by manipulating the training input data involving original and four variants of preprocessed image datasets. There are publicly available datasets with labels for all five stages, but some contain poor‐quality images. In contrast, this algorithm was trained on images from a six‐class DDR dataset, including the class of poor‐quality ungradable images, to enhance the classification performance. The solution was evaluated on the APTOS dataset, containing only ICDRSS classes. Classification results of the ensemble model were presented on two different ensemble convolutional neural network (CNN) models, based on Xception and EfficientNetB4 architectures using two fusion approaches. Our proposed ensemble models outperformed all other single deep learning architectures regarding overall accuracy and Cohen's Kappa, with the best results using the EfficientNetB4 architecture.https://doi.org/10.1049/ipr2.12987biomedical optical imagingcomputer visionconvolutional neural netsimage classificationmedical image processing
spellingShingle Peter Macsik
Jarmila Pavlovicova
Slavomir Kajan
Jozef Goga
Veronika Kurilova
Image preprocessing‐based ensemble deep learning classification of diabetic retinopathy
IET Image Processing
biomedical optical imaging
computer vision
convolutional neural nets
image classification
medical image processing
title Image preprocessing‐based ensemble deep learning classification of diabetic retinopathy
title_full Image preprocessing‐based ensemble deep learning classification of diabetic retinopathy
title_fullStr Image preprocessing‐based ensemble deep learning classification of diabetic retinopathy
title_full_unstemmed Image preprocessing‐based ensemble deep learning classification of diabetic retinopathy
title_short Image preprocessing‐based ensemble deep learning classification of diabetic retinopathy
title_sort image preprocessing based ensemble deep learning classification of diabetic retinopathy
topic biomedical optical imaging
computer vision
convolutional neural nets
image classification
medical image processing
url https://doi.org/10.1049/ipr2.12987
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AT slavomirkajan imagepreprocessingbasedensembledeeplearningclassificationofdiabeticretinopathy
AT jozefgoga imagepreprocessingbasedensembledeeplearningclassificationofdiabeticretinopathy
AT veronikakurilova imagepreprocessingbasedensembledeeplearningclassificationofdiabeticretinopathy