The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning

The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning

Abstract Background Histone acetylation plays an important role in DNA replication and repair because replicating chromatin is subject to dynamic changes in its structures. However, its precise mechanism remains elusive. In this report, we describe roles of the NuA4 acetyltransferase and histone H4...

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Bibliographic Details
Main Authors: Chiaki Noguchi, Tanu Singh, Melissa A. Ziegler, Jasmine D. Peake, Lyne Khair, Ana Aza, Toru M. Nakamura, Eishi Noguchi
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Epigenetics & Chromatin
Subjects:
Histone H4
Acetylation
DNA replication
Replication forks
Chromatin
Schizosaccharomyces pombe
Online Access:http://link.springer.com/article/10.1186/s13072-019-0271-z

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