Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson’s disease

Abstract This article describes pathogenic concepts and factors, in particular glycolipid abnormalities, that create cell dysfunction and synaptic loss in neurodegenerative diseases. By phenocopying lysosomal storage disorders, such as Gaucher disease and related disorders, age- and dose-dependent c...

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Бібліографічні деталі
Автори: Penelope J. Hallett, Simone Engelender, Ole Isacson
Формат: Стаття
Мова:English
Опубліковано: BMC 2019-07-01
Серія:Journal of Neuroinflammation
Предмети:
Онлайн доступ:http://link.springer.com/article/10.1186/s12974-019-1532-2