Postpartum fevers, a rare presentation of secondary hemophagocytic lymphohistiocytosis
Abstract Hemophagocytic lymphohistiocytosis (HLH) is a rare disease of excessive immune system activation. We report a case of HLH in a 20‐year‐old primigravid woman who presented with postpartum fevers. She was successfully treated with dexamethasone and anakinra, a deviation from the HLH‐94 protoc...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-03-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.7070 |
| _version_ | 1797856085725413376 |
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| author | Jacqueline Lee Brian Pham Zarir E. Karanjawala Oyebimpe Adesina |
| author_facet | Jacqueline Lee Brian Pham Zarir E. Karanjawala Oyebimpe Adesina |
| author_sort | Jacqueline Lee |
| collection | DOAJ |
| description | Abstract Hemophagocytic lymphohistiocytosis (HLH) is a rare disease of excessive immune system activation. We report a case of HLH in a 20‐year‐old primigravid woman who presented with postpartum fevers. She was successfully treated with dexamethasone and anakinra, a deviation from the HLH‐94 protocol, to preserve her ability to breastfeed. |
| first_indexed | 2024-04-09T20:35:43Z |
| format | Article |
| id | doaj.art-72430e03f46e45b69f1b29368649e837 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-04-09T20:35:43Z |
| publishDate | 2023-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-72430e03f46e45b69f1b29368649e8372023-03-30T10:21:25ZengWileyClinical Case Reports2050-09042023-03-01113n/an/a10.1002/ccr3.7070Postpartum fevers, a rare presentation of secondary hemophagocytic lymphohistiocytosisJacqueline Lee0Brian Pham1Zarir E. Karanjawala2Oyebimpe Adesina3Department of Internal Medicine University of California Davis School of Medicine Sacramento California USADivision of Hematology and Oncology University of California Davis School of Medicine Sacramento California USADivision of Hematopathology University of California Davis School of Medicine Sacramento California USADivision of Hematology and Oncology University of California Davis School of Medicine Sacramento California USAAbstract Hemophagocytic lymphohistiocytosis (HLH) is a rare disease of excessive immune system activation. We report a case of HLH in a 20‐year‐old primigravid woman who presented with postpartum fevers. She was successfully treated with dexamethasone and anakinra, a deviation from the HLH‐94 protocol, to preserve her ability to breastfeed.https://doi.org/10.1002/ccr3.7070anakinrafever of unknown originhemophagocytic lymphohistiocytosispostpartum fevers |
| spellingShingle | Jacqueline Lee Brian Pham Zarir E. Karanjawala Oyebimpe Adesina Postpartum fevers, a rare presentation of secondary hemophagocytic lymphohistiocytosis Clinical Case Reports anakinra fever of unknown origin hemophagocytic lymphohistiocytosis postpartum fevers |
| title | Postpartum fevers, a rare presentation of secondary hemophagocytic lymphohistiocytosis |
| title_full | Postpartum fevers, a rare presentation of secondary hemophagocytic lymphohistiocytosis |
| title_fullStr | Postpartum fevers, a rare presentation of secondary hemophagocytic lymphohistiocytosis |
| title_full_unstemmed | Postpartum fevers, a rare presentation of secondary hemophagocytic lymphohistiocytosis |
| title_short | Postpartum fevers, a rare presentation of secondary hemophagocytic lymphohistiocytosis |
| title_sort | postpartum fevers a rare presentation of secondary hemophagocytic lymphohistiocytosis |
| topic | anakinra fever of unknown origin hemophagocytic lymphohistiocytosis postpartum fevers |
| url | https://doi.org/10.1002/ccr3.7070 |
| work_keys_str_mv | AT jacquelinelee postpartumfeversararepresentationofsecondaryhemophagocyticlymphohistiocytosis AT brianpham postpartumfeversararepresentationofsecondaryhemophagocyticlymphohistiocytosis AT zarirekaranjawala postpartumfeversararepresentationofsecondaryhemophagocyticlymphohistiocytosis AT oyebimpeadesina postpartumfeversararepresentationofsecondaryhemophagocyticlymphohistiocytosis |