Transcriptome analysis in LRRK2 and idiopathic Parkinson’s disease at different glucose levels
Abstract Type-2 diabetes (T2D) and glucose metabolic imbalances have been linked to neurodegenerative diseases, including Parkinson’s disease (PD). To detect potential effects of different glucose levels on gene expression, by RNA-seq we analyzed the transcriptome of dermal fibroblasts from idiopath...
Main Authors: | Rubén Fernández-Santiago, Anna Esteve-Codina, Manel Fernández, Francesc Valldeoriola, Almudena Sanchez-Gómez, Esteban Muñoz, Yaroslau Compta, Eduardo Tolosa, Mario Ezquerra, María J. Martí |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-12-01
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Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-021-00255-x |
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