Integrative microRNA and mRNA deep-sequencing expression profiling in endemic Burkitt lymphoma

Integrative microRNA and mRNA deep-sequencing expression profiling in endemic Burkitt lymphoma

Abstract Background Burkitt lymphoma (BL) is characterized by overexpression of the c-myc oncogene, which in the vast majority of cases is a consequence of an IGH/MYC translocation. While myc is the seminal event, BL is a complex amalgam of genetic and epigenetic changes causing dysregulation of bot...

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Bibliographic Details
Main Authors: Cliff I. Oduor, Yasin Kaymaz, Kiprotich Chelimo, Juliana A. Otieno, John Michael Ong’echa, Ann M. Moormann, Jeffrey A. Bailey
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Cancer
Subjects:
Endemic Burkitt lymphoma
miRNA
mRNA
RNA sequencing
Lymphomagenesis
Online Access:http://link.springer.com/article/10.1186/s12885-017-3711-9

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