Comparing spatial patterns of 11 common cancers in Mainland China
Abstract Background A stronger spatial clustering of cancer burden indicates stronger environmental and human behavioral effects. However, which common cancers in China have stronger spatial clustering and knowledge gaps regarding the environmental and human behavioral effects have yet to be investi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-08-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-022-13926-y |
| _version_ | 1798038773957656576 |
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| author | Lin Zhang Xia Wan Runhe Shi Peng Gong Yali Si |
| author_facet | Lin Zhang Xia Wan Runhe Shi Peng Gong Yali Si |
| author_sort | Lin Zhang |
| collection | DOAJ |
| description | Abstract Background A stronger spatial clustering of cancer burden indicates stronger environmental and human behavioral effects. However, which common cancers in China have stronger spatial clustering and knowledge gaps regarding the environmental and human behavioral effects have yet to be investigated. This study aimed to compare the spatial clustering degree and hotspot patterns of 11 common cancers in mainland China and discuss the potential environmental and behavioral risks underlying the patterns. Methods Cancer incidence data recorded at 339 registries in 2014 was obtained from the “China Cancer Registry Annual Report 2017”. We calculated the spatial clustering degree of the common cancers using the global Moran’s Index and identified the hotspot patterns using the hotspot analysis. Results We found that esophagus, stomach and liver cancer have a significantly higher spatial clustering degree ( $$p<0.05$$ p < 0.05 ) than others. When by sex, female esophagus, male stomach, male esophagus, male liver and female lung cancer had significantly higher spatial clustering degree ( $$p<0.001$$ p < 0.001 ). The spatial clustering degree of male liver was significantly higher than that of female liver cancer ( $$p<0.001$$ p < 0.001 ), whereas the spatial clustering degree of female lung was significantly higher than that of male lung cancer ( $$p<0.001$$ p < 0.001 ). The high-risk areas of esophagus and stomach cancer were mainly in North China, Huai River Basin, Yangtze River Delta and Shaanxi Province. The hotspots for liver and male liver cancer were mainly in Southeast China and south Hunan. Hotspots of female lung cancer were mainly located in the Pearl River Delta, Shandong, North and Northeast China. The Yangtze River Delta and the Pearl River Delta were high-risk areas for multiple cancers. Conclusions The top highly clustered cancer types in mainland China included esophagus, stomach and liver cancer and, by sex, female esophagus, male stomach, male esophagus, male liver and female lung cancer. Among them, knowledge of their spatial patterns and environmental and behavioral risk factors is generally limited. Potential factors such as unhealthy diets, water pollution and climate factors have been suggested, and further investigation and validation are urgently needed, particularly for male liver cancer. This study identified the knowledge gap in understanding the spatial pattern of cancer burdens in China and offered insights into targeted cancer monitoring and control. |
| first_indexed | 2024-04-11T21:44:57Z |
| format | Article |
| id | doaj.art-724975e5a7e644b0ac3363ebb6211612 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-04-11T21:44:57Z |
| publishDate | 2022-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-724975e5a7e644b0ac3363ebb62116122022-12-22T04:01:26ZengBMCBMC Public Health1471-24582022-08-0122111210.1186/s12889-022-13926-yComparing spatial patterns of 11 common cancers in Mainland ChinaLin Zhang0Xia Wan1Runhe Shi2Peng Gong3Yali Si4Department of Earth System Science, Ministry of Education Key Laboratory for Earth System Modeling, Institute for Global Change Studies, Tsinghua UniversityInstitute of Basic Medical Sciences, Chinese Academy of Medical Sciences and School of Basic Medicine, Peking Union Medical CollegeKey Laboratory of Geographic Information Science, Ministry of Education, East China Normal UniversityDepartment of Geography and Department of Earth Sciences, University of HongkongInstitute of Environmental Sciences CML, Leiden UniversityAbstract Background A stronger spatial clustering of cancer burden indicates stronger environmental and human behavioral effects. However, which common cancers in China have stronger spatial clustering and knowledge gaps regarding the environmental and human behavioral effects have yet to be investigated. This study aimed to compare the spatial clustering degree and hotspot patterns of 11 common cancers in mainland China and discuss the potential environmental and behavioral risks underlying the patterns. Methods Cancer incidence data recorded at 339 registries in 2014 was obtained from the “China Cancer Registry Annual Report 2017”. We calculated the spatial clustering degree of the common cancers using the global Moran’s Index and identified the hotspot patterns using the hotspot analysis. Results We found that esophagus, stomach and liver cancer have a significantly higher spatial clustering degree ( $$p<0.05$$ p < 0.05 ) than others. When by sex, female esophagus, male stomach, male esophagus, male liver and female lung cancer had significantly higher spatial clustering degree ( $$p<0.001$$ p < 0.001 ). The spatial clustering degree of male liver was significantly higher than that of female liver cancer ( $$p<0.001$$ p < 0.001 ), whereas the spatial clustering degree of female lung was significantly higher than that of male lung cancer ( $$p<0.001$$ p < 0.001 ). The high-risk areas of esophagus and stomach cancer were mainly in North China, Huai River Basin, Yangtze River Delta and Shaanxi Province. The hotspots for liver and male liver cancer were mainly in Southeast China and south Hunan. Hotspots of female lung cancer were mainly located in the Pearl River Delta, Shandong, North and Northeast China. The Yangtze River Delta and the Pearl River Delta were high-risk areas for multiple cancers. Conclusions The top highly clustered cancer types in mainland China included esophagus, stomach and liver cancer and, by sex, female esophagus, male stomach, male esophagus, male liver and female lung cancer. Among them, knowledge of their spatial patterns and environmental and behavioral risk factors is generally limited. Potential factors such as unhealthy diets, water pollution and climate factors have been suggested, and further investigation and validation are urgently needed, particularly for male liver cancer. This study identified the knowledge gap in understanding the spatial pattern of cancer burdens in China and offered insights into targeted cancer monitoring and control.https://doi.org/10.1186/s12889-022-13926-yCancer burdenSpatial patternSpatial clusteringHotspotsSpatial analysis |
| spellingShingle | Lin Zhang Xia Wan Runhe Shi Peng Gong Yali Si Comparing spatial patterns of 11 common cancers in Mainland China BMC Public Health Cancer burden Spatial pattern Spatial clustering Hotspots Spatial analysis |
| title | Comparing spatial patterns of 11 common cancers in Mainland China |
| title_full | Comparing spatial patterns of 11 common cancers in Mainland China |
| title_fullStr | Comparing spatial patterns of 11 common cancers in Mainland China |
| title_full_unstemmed | Comparing spatial patterns of 11 common cancers in Mainland China |
| title_short | Comparing spatial patterns of 11 common cancers in Mainland China |
| title_sort | comparing spatial patterns of 11 common cancers in mainland china |
| topic | Cancer burden Spatial pattern Spatial clustering Hotspots Spatial analysis |
| url | https://doi.org/10.1186/s12889-022-13926-y |
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