Surgical tactics and treatment results at spinal lymphomas
The purpose — to study features of lymphomas affecting spinal cord and it’s membranes, to develop rational tactics for their treatment.Material and methods. 9 patients with spinal lymphomas were examined. All patients have been operated, the diagnosis was verified histologically. Preopera...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Romodanov Neurosurgery Institute
2014-06-01
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| Series: | Ukrainian Neurosurgical Journal |
| Online Access: | https://theunj.org/article/view/51298 |
| _version_ | 1797348292339695616 |
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| author | Eugene Slynko Anatoliy Pastushin Tatyana Malysheva Oksana Chernenko |
| author_facet | Eugene Slynko Anatoliy Pastushin Tatyana Malysheva Oksana Chernenko |
| author_sort | Eugene Slynko |
| collection | DOAJ |
| description |
The purpose — to study features of lymphomas affecting spinal cord and it’s membranes, to develop rational tactics for their treatment.Material and methods. 9 patients with spinal lymphomas were examined. All patients have been operated, the diagnosis was verified histologically. Preoperative diagnostics was based on clinical data and neurological examination, X-ray, MRI. Electroneuromyography was performed in 5 patients, bone scintigraphy — in 3.Results. Two main localization of lymphomas were identified: I — intramedullar lesion, and II — lesion of dura mater of the spinal cord with epidural, subdural or epi-subdural spread. In 3 cases intramedullar lesion was revealed, in 6 — lesion of dura mater of the spinal cord.Conclusions. There are tumors that primary affects the spinal cord or it’s dura mater. Tumors affecting the spinal cord, non-Hodgkin’s lymphomas as a rule are the primary. Tumors affecting spinal dura mater are Hodgkin’s lymphoma, and usually are the secondary, they manifested after prolonged conservative treatment. The histological diagnosis of lymphoma should be confirmed by immunohistochemical studies. Tactics of treatment at spinal lymphomas with neurological manifestations should be directed to their removal, decompression of spinal cord followed by radiotherapy, chemotherapy and corticosteroid therapy if necessary. |
| first_indexed | 2024-03-08T12:03:43Z |
| format | Article |
| id | doaj.art-724987f7e3c241c0adf793fea1dbcf84 |
| institution | Directory Open Access Journal |
| issn | 2663-9084 2663-9092 |
| language | English |
| last_indexed | 2024-03-08T12:03:43Z |
| publishDate | 2014-06-01 |
| publisher | Romodanov Neurosurgery Institute |
| record_format | Article |
| series | Ukrainian Neurosurgical Journal |
| spelling | doaj.art-724987f7e3c241c0adf793fea1dbcf842024-01-23T13:31:38ZengRomodanov Neurosurgery InstituteUkrainian Neurosurgical Journal2663-90842663-90922014-06-012293510.25305/unj.51298Surgical tactics and treatment results at spinal lymphomasEugene Slynko0Anatoliy Pastushin1Tatyana Malysheva2Oksana Chernenko3Spinal Department, Romodanov Neurosurgery Institute, Kiev, UkraineSpinal Department, Romodanov Neurosurgery Institute, Kiev, UkraineDepartment of Pathomorphology, Romodanov Neurosurgery Institute, Kiev, UkraineDepartment of Pathomorphology, Romodanov Neurosurgery Institute, Kiev, Ukraine The purpose — to study features of lymphomas affecting spinal cord and it’s membranes, to develop rational tactics for their treatment.Material and methods. 9 patients with spinal lymphomas were examined. All patients have been operated, the diagnosis was verified histologically. Preoperative diagnostics was based on clinical data and neurological examination, X-ray, MRI. Electroneuromyography was performed in 5 patients, bone scintigraphy — in 3.Results. Two main localization of lymphomas were identified: I — intramedullar lesion, and II — lesion of dura mater of the spinal cord with epidural, subdural or epi-subdural spread. In 3 cases intramedullar lesion was revealed, in 6 — lesion of dura mater of the spinal cord.Conclusions. There are tumors that primary affects the spinal cord or it’s dura mater. Tumors affecting the spinal cord, non-Hodgkin’s lymphomas as a rule are the primary. Tumors affecting spinal dura mater are Hodgkin’s lymphoma, and usually are the secondary, they manifested after prolonged conservative treatment. The histological diagnosis of lymphoma should be confirmed by immunohistochemical studies. Tactics of treatment at spinal lymphomas with neurological manifestations should be directed to their removal, decompression of spinal cord followed by radiotherapy, chemotherapy and corticosteroid therapy if necessary.https://theunj.org/article/view/51298 |
| spellingShingle | Eugene Slynko Anatoliy Pastushin Tatyana Malysheva Oksana Chernenko Surgical tactics and treatment results at spinal lymphomas Ukrainian Neurosurgical Journal |
| title | Surgical tactics and treatment results at spinal lymphomas |
| title_full | Surgical tactics and treatment results at spinal lymphomas |
| title_fullStr | Surgical tactics and treatment results at spinal lymphomas |
| title_full_unstemmed | Surgical tactics and treatment results at spinal lymphomas |
| title_short | Surgical tactics and treatment results at spinal lymphomas |
| title_sort | surgical tactics and treatment results at spinal lymphomas |
| url | https://theunj.org/article/view/51298 |
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