Structural investigation of Ayurveda Lauha (Iron) Bhasma

In Ayurveda, ‘Lauha’ (Iron) Bhasma is primarily used to cure diseases related to iron deficiency in humans. It is produced from purified raw metallic iron using a combination of multi-step traditional preparation processes described in the Ayurveda literature. Here, we present the results of structu...

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Main Authors: M.K. Tiwari, Arjun Singh, Ajay Khooha, U.K. Goutam
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Journal of Ayurveda and Integrative Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0975947623000050
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author M.K. Tiwari
Arjun Singh
Ajay Khooha
U.K. Goutam
author_facet M.K. Tiwari
Arjun Singh
Ajay Khooha
U.K. Goutam
author_sort M.K. Tiwari
collection DOAJ
description In Ayurveda, ‘Lauha’ (Iron) Bhasma is primarily used to cure diseases related to iron deficiency in humans. It is produced from purified raw metallic iron using a combination of multi-step traditional preparation processes described in the Ayurveda literature. Here, we present the results of structural investigation performed on the medicinal grade ‘Lauha’ Bhasma using various X-ray based techniques. Our results indicate that after several rounds of heating and cooling in specific conditions following the Ayurvedic preparation procedure, metallic iron eventually converts to a natural iron-oxide mineral belonging to the magnetite group. Scanning electron microscopy (SEM) and X-ray standing wave assisted fluorescence measurements carried out on powdered Bhasma specimen reveal that the magnetite micro-particles in the Bhasma specimen are usually present in the form of agglomerates of nano-particles. We anticipate that the Ayurvedic Lauha Bhasma has great potential for noninvasive localized target killing of cancer cells, particularly in sensitive parts of the human body such as the brain, spinal cord, and lungs, via necrosis by application of an alternating external magnetic field or photo electron generation through X-rays.
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spelling doaj.art-724a9c5d0f974c2e8eff8aeb5385d6252023-06-01T04:35:11ZengElsevierJournal of Ayurveda and Integrative Medicine0975-94762023-03-01142100690Structural investigation of Ayurveda Lauha (Iron) BhasmaM.K. Tiwari0Arjun Singh1Ajay Khooha2U.K. Goutam3Accelerator Physics and Synchrotrons Utilization Division, Raja Ramanna Centre for Advanced Technology, Indore, 452013, India; Homi Bhabha National Institute, Anushaktinagar, Mumbai, 400094, India; Corresponding author.Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, New Delhi, 110058, IndiaAccelerator Physics and Synchrotrons Utilization Division, Raja Ramanna Centre for Advanced Technology, Indore, 452013, IndiaTechnical Physics Division, Bhabha Atomic Research Centre, Mumbai, 400085, IndiaIn Ayurveda, ‘Lauha’ (Iron) Bhasma is primarily used to cure diseases related to iron deficiency in humans. It is produced from purified raw metallic iron using a combination of multi-step traditional preparation processes described in the Ayurveda literature. Here, we present the results of structural investigation performed on the medicinal grade ‘Lauha’ Bhasma using various X-ray based techniques. Our results indicate that after several rounds of heating and cooling in specific conditions following the Ayurvedic preparation procedure, metallic iron eventually converts to a natural iron-oxide mineral belonging to the magnetite group. Scanning electron microscopy (SEM) and X-ray standing wave assisted fluorescence measurements carried out on powdered Bhasma specimen reveal that the magnetite micro-particles in the Bhasma specimen are usually present in the form of agglomerates of nano-particles. We anticipate that the Ayurvedic Lauha Bhasma has great potential for noninvasive localized target killing of cancer cells, particularly in sensitive parts of the human body such as the brain, spinal cord, and lungs, via necrosis by application of an alternating external magnetic field or photo electron generation through X-rays.http://www.sciencedirect.com/science/article/pii/S0975947623000050Ayurvedic BhasmaNanomaterialsX-ray fluorescenceTrace element analysisSynchrotron radiation
spellingShingle M.K. Tiwari
Arjun Singh
Ajay Khooha
U.K. Goutam
Structural investigation of Ayurveda Lauha (Iron) Bhasma
Journal of Ayurveda and Integrative Medicine
Ayurvedic Bhasma
Nanomaterials
X-ray fluorescence
Trace element analysis
Synchrotron radiation
title Structural investigation of Ayurveda Lauha (Iron) Bhasma
title_full Structural investigation of Ayurveda Lauha (Iron) Bhasma
title_fullStr Structural investigation of Ayurveda Lauha (Iron) Bhasma
title_full_unstemmed Structural investigation of Ayurveda Lauha (Iron) Bhasma
title_short Structural investigation of Ayurveda Lauha (Iron) Bhasma
title_sort structural investigation of ayurveda lauha iron bhasma
topic Ayurvedic Bhasma
Nanomaterials
X-ray fluorescence
Trace element analysis
Synchrotron radiation
url http://www.sciencedirect.com/science/article/pii/S0975947623000050
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