Preparation of glucopyranosylamines in the pipeline reactor(管道化制备吡喃葡萄糖胺类化合物)
以葡萄糖和有机胺为原料,采用管道化反应器合成了 3种吡喃葡萄糖胺类化合物：N-（2-羟乙基）-β-D-吡喃葡萄糖胺、N-丁基-β-D-吡喃葡萄糖胺和N-环己基-β-D-吡喃葡萄糖胺,收率分别达到94.3%、98.1%和95.7%,所得产品纯度高,色泽好,产品分别通过ESI-MS、IR和1H-NMR进行了表征.并重点研究了N-（2-羟乙基）-β-D-吡喃葡萄糖胺的合成工艺,较优的工艺条件为：甲醇水溶液作为反应溶剂,乙醇胺与葡萄糖摩尔比为1.1,反应温度为70 ℃,反应压力为1.0~2.0 MPa....
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| Format: | Article |
| Language: | zho |
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Zhejiang University Press
2009-11-01
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| Series: | Zhejiang Daxue xuebao. Lixue ban |
| Subjects: | |
| Online Access: | https://doi.org/10.3785/j.issn.1008-9497.2009.06.018 |
| _version_ | 1827303286105964544 |
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| author | WANGShuai(王帅) QIANChao(钱超) LIUZhen-xing(刘振兴) CHENXin-zhi(陈新志) |
| author_facet | WANGShuai(王帅) QIANChao(钱超) LIUZhen-xing(刘振兴) CHENXin-zhi(陈新志) |
| author_sort | WANGShuai(王帅) |
| collection | DOAJ |
| description | 以葡萄糖和有机胺为原料,采用管道化反应器合成了 3种吡喃葡萄糖胺类化合物：N-（2-羟乙基）-β-D-吡喃葡萄糖胺、N-丁基-β-D-吡喃葡萄糖胺和N-环己基-β-D-吡喃葡萄糖胺,收率分别达到94.3%、98.1%和95.7%,所得产品纯度高,色泽好,产品分别通过ESI-MS、IR和1H-NMR进行了表征.并重点研究了N-（2-羟乙基）-β-D-吡喃葡萄糖胺的合成工艺,较优的工艺条件为：甲醇水溶液作为反应溶剂,乙醇胺与葡萄糖摩尔比为1.1,反应温度为70 ℃,反应压力为1.0~2.0 MPa. |
| first_indexed | 2024-04-24T16:59:15Z |
| format | Article |
| id | doaj.art-72512443de684ee4856009bb5b8683c8 |
| institution | Directory Open Access Journal |
| issn | 1008-9497 |
| language | zho |
| last_indexed | 2024-04-24T16:59:15Z |
| publishDate | 2009-11-01 |
| publisher | Zhejiang University Press |
| record_format | Article |
| series | Zhejiang Daxue xuebao. Lixue ban |
| spelling | doaj.art-72512443de684ee4856009bb5b8683c82024-03-29T01:58:27ZzhoZhejiang University PressZhejiang Daxue xuebao. Lixue ban1008-94972009-11-0136668368610.3785/j.issn.1008-9497.2009.06.018Preparation of glucopyranosylamines in the pipeline reactor(管道化制备吡喃葡萄糖胺类化合物)WANGShuai(王帅)0QIANChao(钱超)1LIUZhen-xing(刘振兴)2CHENXin-zhi(陈新志)College of Materials Science and Chemical Engineering, Zhej iang University, Hangzhou 310027, China(浙江大学材料与化学工程学院，浙江 杭州 310027)College of Materials Science and Chemical Engineering, Zhej iang University, Hangzhou 310027, China(浙江大学材料与化学工程学院，浙江 杭州 310027)College of Materials Science and Chemical Engineering, Zhej iang University, Hangzhou 310027, China(浙江大学材料与化学工程学院，浙江 杭州 310027)以葡萄糖和有机胺为原料,采用管道化反应器合成了 3种吡喃葡萄糖胺类化合物：N-（2-羟乙基）-β-D-吡喃葡萄糖胺、N-丁基-β-D-吡喃葡萄糖胺和N-环己基-β-D-吡喃葡萄糖胺,收率分别达到94.3%、98.1%和95.7%,所得产品纯度高,色泽好,产品分别通过ESI-MS、IR和1H-NMR进行了表征.并重点研究了N-（2-羟乙基）-β-D-吡喃葡萄糖胺的合成工艺,较优的工艺条件为：甲醇水溶液作为反应溶剂,乙醇胺与葡萄糖摩尔比为1.1,反应温度为70 ℃,反应压力为1.0~2.0 MPa.https://doi.org/10.3785/j.issn.1008-9497.2009.06.018葡萄糖吡喃葡萄糖胺管道化反应器 |
| spellingShingle | WANGShuai(王帅) QIANChao(钱超) LIUZhen-xing(刘振兴) CHENXin-zhi(陈新志) Preparation of glucopyranosylamines in the pipeline reactor(管道化制备吡喃葡萄糖胺类化合物) Zhejiang Daxue xuebao. Lixue ban 葡萄糖 吡喃葡萄糖胺 管道化反应器 |
| title | Preparation of glucopyranosylamines in the pipeline reactor(管道化制备吡喃葡萄糖胺类化合物) |
| title_full | Preparation of glucopyranosylamines in the pipeline reactor(管道化制备吡喃葡萄糖胺类化合物) |
| title_fullStr | Preparation of glucopyranosylamines in the pipeline reactor(管道化制备吡喃葡萄糖胺类化合物) |
| title_full_unstemmed | Preparation of glucopyranosylamines in the pipeline reactor(管道化制备吡喃葡萄糖胺类化合物) |
| title_short | Preparation of glucopyranosylamines in the pipeline reactor(管道化制备吡喃葡萄糖胺类化合物) |
| title_sort | preparation of glucopyranosylamines in the pipeline reactor 管道化制备吡喃葡萄糖胺类化合物 |
| topic | 葡萄糖 吡喃葡萄糖胺 管道化反应器 |
| url | https://doi.org/10.3785/j.issn.1008-9497.2009.06.018 |
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