Ginkgo biloba induced mood dysregulation: a case report

Abstract Background Impairment of cognitive function as well as negative symptom is the major factor causing the decline of a patient’s functioning in chronic stages of schizophrenia. However, until now, there were no definite treatment options that could effectively reduce the impairment. Case pres...

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Main Authors: Seung Sun Rho, Young Sup Woo, Won-Myong Bahk
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12906-018-2081-4
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author Seung Sun Rho
Young Sup Woo
Won-Myong Bahk
author_facet Seung Sun Rho
Young Sup Woo
Won-Myong Bahk
author_sort Seung Sun Rho
collection DOAJ
description Abstract Background Impairment of cognitive function as well as negative symptom is the major factor causing the decline of a patient’s functioning in chronic stages of schizophrenia. However, until now, there were no definite treatment options that could effectively reduce the impairment. Case presentation We report a case of mood dysregulation associated with use of Ginkgo biloba in a patient with schizophrenia. After Ginkgo biloba was given, the patient experienced cluster symptoms of mood dysregulation including irritability, difficulty in controlling anger, agitation and restlessness. We estimated the possibility as “probable” according to Naranjo scale considering circumstantial evidence. Conclusions This case suggests that Ginkgo biloba may have caused mood dysregulation in this patient. Although it is generally accepted as safe, more attention should be given to the adverse effect when treating with Ginkgo biloba.
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spelling doaj.art-7251631548b04f8c9fea46a12a070d172022-12-21T23:52:34ZengBMCBMC Complementary and Alternative Medicine1472-68822018-01-011811410.1186/s12906-018-2081-4Ginkgo biloba induced mood dysregulation: a case reportSeung Sun Rho0Young Sup Woo1Won-Myong Bahk2Department of Psychiatry, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of KoreaDepartment of Psychiatry, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of KoreaDepartment of Psychiatry, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of KoreaAbstract Background Impairment of cognitive function as well as negative symptom is the major factor causing the decline of a patient’s functioning in chronic stages of schizophrenia. However, until now, there were no definite treatment options that could effectively reduce the impairment. Case presentation We report a case of mood dysregulation associated with use of Ginkgo biloba in a patient with schizophrenia. After Ginkgo biloba was given, the patient experienced cluster symptoms of mood dysregulation including irritability, difficulty in controlling anger, agitation and restlessness. We estimated the possibility as “probable” according to Naranjo scale considering circumstantial evidence. Conclusions This case suggests that Ginkgo biloba may have caused mood dysregulation in this patient. Although it is generally accepted as safe, more attention should be given to the adverse effect when treating with Ginkgo biloba.http://link.springer.com/article/10.1186/s12906-018-2081-4Ginkgo bilobaMood dysregulationSchizophrenia
spellingShingle Seung Sun Rho
Young Sup Woo
Won-Myong Bahk
Ginkgo biloba induced mood dysregulation: a case report
BMC Complementary and Alternative Medicine
Ginkgo biloba
Mood dysregulation
Schizophrenia
title Ginkgo biloba induced mood dysregulation: a case report
title_full Ginkgo biloba induced mood dysregulation: a case report
title_fullStr Ginkgo biloba induced mood dysregulation: a case report
title_full_unstemmed Ginkgo biloba induced mood dysregulation: a case report
title_short Ginkgo biloba induced mood dysregulation: a case report
title_sort ginkgo biloba induced mood dysregulation a case report
topic Ginkgo biloba
Mood dysregulation
Schizophrenia
url http://link.springer.com/article/10.1186/s12906-018-2081-4
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