C1Q MODULATION OF ANTIBODY DEPENDENT ENHANCEMENT OF DENGUE VIRUS INFECTION IN HUMAN MYELOID CELL LINES IS DEPENDENT ON CELL TYPE AND ANTIBODY SPECIFICITY
Intro: Antibodies play a critical role in protection and pathogenesis of dengue virus (DENV). In the presence of preexisting antibodies that bind but do not neutralize viral particles, virus-antibody immune complexes are internalized by Fcγ receptor (FcγR)-expressing cells, generating increased vira...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-05-01
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| Series: | International Journal of Infectious Diseases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S120197122300437X |