The global research of microbiota in colorectal cancer screening: a bibliometric and visualization analysis
AimsWe conducted bibliometric and visualization analyses to evaluate the current research status, hotspots, and trends related to the human microbiota markers in colorectal cancer screening.MethodsThe related studies were acquired from the Web of Science Core Collection (WoSCC) database on 5 January...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-05-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1169369/full |
| _version_ | 1827953685331705856 |
|---|---|
| author | Junhai Zhen Chuan Liu Fei Liao Jixiang Zhang Huabing Xie Cheng Tan Weiguo Dong |
| author_facet | Junhai Zhen Chuan Liu Fei Liao Jixiang Zhang Huabing Xie Cheng Tan Weiguo Dong |
| author_sort | Junhai Zhen |
| collection | DOAJ |
| description | AimsWe conducted bibliometric and visualization analyses to evaluate the current research status, hotspots, and trends related to the human microbiota markers in colorectal cancer screening.MethodsThe related studies were acquired from the Web of Science Core Collection (WoSCC) database on 5 January 2023. Analyses of the co-occurrence and cooperation relationships between the cited authors, institutions, countries/regions, cited journals, cited articles, and keywords in the studies were carried out using CiteSpace 5.8.R3 software and the Online Analysis platform of Literature Metrology. Additionally, relevant knowledge graphs were drawn to perform visualization analyses; a keywords cluster analysis and a burst analysis were also conducted.ResultsAfter analyzing 700 relevant articles, this bibliometric analysis found that the annual publications showed an increasing trend from 1992 to 2022. Yu Jun from the Chinese University of Hong Kong had the highest cumulative number of publications, whereas Shanghai Jiao Tong University was the most productive institution. China and the USA have contributed the largest number of studies. The keywords frequency analysis demonstrated that “colorectal cancer,” “gut microbiota,” “Fusobacterium nucleatum,” “risk,” and “microbiota” were the most frequent keywords, and the keywords cluster analysis found that the current hotspots were as follows: (a) the precancerous lesions of colorectal cancer (CRC) that need to be screened, such as inflammatory bowel disease (IBD) and advanced adenoma, (b) the gut-derived microbiome for CRC screening, and (c) the early detection of CRC. The burst analysis further showed that the combination of microbiomics with metabolomics might be the future research trend in the field of CRC screening.ConclusionThe findings of the current bibliometric analysis firstly provide an insight into the current research status, hotspots, and future trends in the field of CRC screening based on the microbiome; the research in this field is becoming more in-depth and diversified. Some human microbiota markers, especially “Fusobacterium nucleatum,” are promising biomarkers in CRC screening, and a future hotspot might be the combined analysis of microbiomics and metabolomics for CRC risk screening. |
| first_indexed | 2024-04-09T14:17:24Z |
| format | Article |
| id | doaj.art-7256d08587704492a7f9da4683b14cfd |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-09T14:17:24Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-7256d08587704492a7f9da4683b14cfd2023-05-05T06:06:23ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-05-011310.3389/fonc.2023.11693691169369The global research of microbiota in colorectal cancer screening: a bibliometric and visualization analysisJunhai Zhen0Chuan Liu1Fei Liao2Jixiang Zhang3Huabing Xie4Cheng Tan5Weiguo Dong6Department of General Practice, Renmin Hospital of Wuhan University, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, ChinaDepartment of General Practice, Renmin Hospital of Wuhan University, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, ChinaDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, Hubei, ChinaAimsWe conducted bibliometric and visualization analyses to evaluate the current research status, hotspots, and trends related to the human microbiota markers in colorectal cancer screening.MethodsThe related studies were acquired from the Web of Science Core Collection (WoSCC) database on 5 January 2023. Analyses of the co-occurrence and cooperation relationships between the cited authors, institutions, countries/regions, cited journals, cited articles, and keywords in the studies were carried out using CiteSpace 5.8.R3 software and the Online Analysis platform of Literature Metrology. Additionally, relevant knowledge graphs were drawn to perform visualization analyses; a keywords cluster analysis and a burst analysis were also conducted.ResultsAfter analyzing 700 relevant articles, this bibliometric analysis found that the annual publications showed an increasing trend from 1992 to 2022. Yu Jun from the Chinese University of Hong Kong had the highest cumulative number of publications, whereas Shanghai Jiao Tong University was the most productive institution. China and the USA have contributed the largest number of studies. The keywords frequency analysis demonstrated that “colorectal cancer,” “gut microbiota,” “Fusobacterium nucleatum,” “risk,” and “microbiota” were the most frequent keywords, and the keywords cluster analysis found that the current hotspots were as follows: (a) the precancerous lesions of colorectal cancer (CRC) that need to be screened, such as inflammatory bowel disease (IBD) and advanced adenoma, (b) the gut-derived microbiome for CRC screening, and (c) the early detection of CRC. The burst analysis further showed that the combination of microbiomics with metabolomics might be the future research trend in the field of CRC screening.ConclusionThe findings of the current bibliometric analysis firstly provide an insight into the current research status, hotspots, and future trends in the field of CRC screening based on the microbiome; the research in this field is becoming more in-depth and diversified. Some human microbiota markers, especially “Fusobacterium nucleatum,” are promising biomarkers in CRC screening, and a future hotspot might be the combined analysis of microbiomics and metabolomics for CRC risk screening.https://www.frontiersin.org/articles/10.3389/fonc.2023.1169369/fullmicrobiotacolorectal cancerscreeningbibliometriccitespace |
| spellingShingle | Junhai Zhen Chuan Liu Fei Liao Jixiang Zhang Huabing Xie Cheng Tan Weiguo Dong The global research of microbiota in colorectal cancer screening: a bibliometric and visualization analysis Frontiers in Oncology microbiota colorectal cancer screening bibliometric citespace |
| title | The global research of microbiota in colorectal cancer screening: a bibliometric and visualization analysis |
| title_full | The global research of microbiota in colorectal cancer screening: a bibliometric and visualization analysis |
| title_fullStr | The global research of microbiota in colorectal cancer screening: a bibliometric and visualization analysis |
| title_full_unstemmed | The global research of microbiota in colorectal cancer screening: a bibliometric and visualization analysis |
| title_short | The global research of microbiota in colorectal cancer screening: a bibliometric and visualization analysis |
| title_sort | global research of microbiota in colorectal cancer screening a bibliometric and visualization analysis |
| topic | microbiota colorectal cancer screening bibliometric citespace |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1169369/full |
| work_keys_str_mv | AT junhaizhen theglobalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT chuanliu theglobalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT feiliao theglobalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT jixiangzhang theglobalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT huabingxie theglobalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT chengtan theglobalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT weiguodong theglobalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT junhaizhen globalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT chuanliu globalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT feiliao globalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT jixiangzhang globalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT huabingxie globalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT chengtan globalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis AT weiguodong globalresearchofmicrobiotaincolorectalcancerscreeningabibliometricandvisualizationanalysis |