Gut Microbes in Immunoglobulin A Nephropathy and Their Potential Therapeutic Applications
Microbial ecosystem consists of a complex community of bacterial interactions and its host microenvironment (tissue, cell, metabolite). Because the interaction between gut microbiota and host involves many diseases and seriously affects human health, the study of the interaction mechanism between gu...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.823267/full |
| _version_ | 1811235294191550464 |
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| author | Yi Wang Lingling Tian Lin Sun Wenjing Zhou Wenqiang Zhi Jianbo Qing Yasin Abdi Saed Lina Dong Xiadong Zhang Yafeng Li Yafeng Li Yafeng Li Yafeng Li |
| author_facet | Yi Wang Lingling Tian Lin Sun Wenjing Zhou Wenqiang Zhi Jianbo Qing Yasin Abdi Saed Lina Dong Xiadong Zhang Yafeng Li Yafeng Li Yafeng Li Yafeng Li |
| author_sort | Yi Wang |
| collection | DOAJ |
| description | Microbial ecosystem consists of a complex community of bacterial interactions and its host microenvironment (tissue, cell, metabolite). Because the interaction between gut microbiota and host involves many diseases and seriously affects human health, the study of the interaction mechanism between gut microbiota and host has attracted great attention. The gut microbiome is made up of 100 trillion bacteria that have both beneficial and adverse effects on human health. The development of IgA Nephropathy results in changes in the intestinal microbial ecosystem that affect host physiology and health. Similarly, changes in intestinal microbiota also affect the development of IgA Nephropathy. Thus, the gut microbiome represents a novel therapeutic target for improving the outcome of IgA Nephropathy, including hematuria symptoms and disease progression. In this review, we summarize the effect of intestinal microbiota on IgA Nephropathy in recent years and it has been clarified that the intestinal microbiota has a great influence on the pathogenesis and treatment of IgA Nephropathy. |
| first_indexed | 2024-04-12T11:48:23Z |
| format | Article |
| id | doaj.art-7259b7e17f3b4805923280d1defdfb67 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-12T11:48:23Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-7259b7e17f3b4805923280d1defdfb672022-12-22T03:34:15ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-05-01910.3389/fmed.2022.823267823267Gut Microbes in Immunoglobulin A Nephropathy and Their Potential Therapeutic ApplicationsYi Wang0Lingling Tian1Lin Sun2Wenjing Zhou3Wenqiang Zhi4Jianbo Qing5Yasin Abdi Saed6Lina Dong7Xiadong Zhang8Yafeng Li9Yafeng Li10Yafeng Li11Yafeng Li12The Third Clinical College, Shanxi University of Chinese Medicine, Taiyuan, ChinaThe Third Clinical College, Shanxi University of Chinese Medicine, Taiyuan, ChinaCollege of Traditional Chinese Medicine and Food Engineering, Shanxi University of Chinese Medicine, Jinzhong, ChinaSchool of Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, ChinaThe Fifth Clinical Medical College of Shanxi Medical University, Taiyuan, ChinaThe Fifth Clinical Medical College of Shanxi Medical University, Taiyuan, ChinaDepartment of Nephrology, Shanxi Provincial People's Hospital (Fifth Hospital) of Shanxi Medical University, Taiyuan, ChinaCore Laboratory, Shanxi Provincial People's Hospital (Fifth Hospital) of Shanxi Medical University, Taiyuan, ChinaCore Laboratory, Shanxi Provincial People's Hospital (Fifth Hospital) of Shanxi Medical University, Taiyuan, ChinaDepartment of Nephrology, Shanxi Provincial People's Hospital (Fifth Hospital) of Shanxi Medical University, Taiyuan, ChinaCore Laboratory, Shanxi Provincial People's Hospital (Fifth Hospital) of Shanxi Medical University, Taiyuan, ChinaShanxi Provincial Key Laboratory of Kidney Disease, Taiyuan, ChinaAcademy of Microbial Ecology, Shanxi Medical University, Taiyuan, ChinaMicrobial ecosystem consists of a complex community of bacterial interactions and its host microenvironment (tissue, cell, metabolite). Because the interaction between gut microbiota and host involves many diseases and seriously affects human health, the study of the interaction mechanism between gut microbiota and host has attracted great attention. The gut microbiome is made up of 100 trillion bacteria that have both beneficial and adverse effects on human health. The development of IgA Nephropathy results in changes in the intestinal microbial ecosystem that affect host physiology and health. Similarly, changes in intestinal microbiota also affect the development of IgA Nephropathy. Thus, the gut microbiome represents a novel therapeutic target for improving the outcome of IgA Nephropathy, including hematuria symptoms and disease progression. In this review, we summarize the effect of intestinal microbiota on IgA Nephropathy in recent years and it has been clarified that the intestinal microbiota has a great influence on the pathogenesis and treatment of IgA Nephropathy.https://www.frontiersin.org/articles/10.3389/fmed.2022.823267/fullgut microbiotaIgA nephropathygut-kidney axispathogenesistherapeutic applications |
| spellingShingle | Yi Wang Lingling Tian Lin Sun Wenjing Zhou Wenqiang Zhi Jianbo Qing Yasin Abdi Saed Lina Dong Xiadong Zhang Yafeng Li Yafeng Li Yafeng Li Yafeng Li Gut Microbes in Immunoglobulin A Nephropathy and Their Potential Therapeutic Applications Frontiers in Medicine gut microbiota IgA nephropathy gut-kidney axis pathogenesis therapeutic applications |
| title | Gut Microbes in Immunoglobulin A Nephropathy and Their Potential Therapeutic Applications |
| title_full | Gut Microbes in Immunoglobulin A Nephropathy and Their Potential Therapeutic Applications |
| title_fullStr | Gut Microbes in Immunoglobulin A Nephropathy and Their Potential Therapeutic Applications |
| title_full_unstemmed | Gut Microbes in Immunoglobulin A Nephropathy and Their Potential Therapeutic Applications |
| title_short | Gut Microbes in Immunoglobulin A Nephropathy and Their Potential Therapeutic Applications |
| title_sort | gut microbes in immunoglobulin a nephropathy and their potential therapeutic applications |
| topic | gut microbiota IgA nephropathy gut-kidney axis pathogenesis therapeutic applications |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.823267/full |
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