Intracranial medulloblastoma as the cause of progressive ataxia in a 6‐month‐old draft horse cross gelding
Abstract We describe the unique clinical presentation of a central nervous system neoplasm in a 6‐month‐old draft horse cross gelding. Based on the neurologic examination at admission, neurolocalization was most consistent with a mildly asymmetric cervical, multifocal, or diffuse myelopathy. Mild ve...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Journal of Veterinary Internal Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jvim.16592 |
| _version_ | 1797938054232539136 |
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| author | Megan Palmisano Susan Bender Amy L. Johnson |
| author_facet | Megan Palmisano Susan Bender Amy L. Johnson |
| author_sort | Megan Palmisano |
| collection | DOAJ |
| description | Abstract We describe the unique clinical presentation of a central nervous system neoplasm in a 6‐month‐old draft horse cross gelding. Based on the neurologic examination at admission, neurolocalization was most consistent with a mildly asymmetric cervical, multifocal, or diffuse myelopathy. Mild vestibular involvement also was considered, but no cranial nerve deficits were observed. The gelding was negative for Sarcocystis neurona or Neospora hughesi based on paired serum and cerebrospinal fluid (CSF) samples analyzed, with no evidence of cervical compression based on contrast myelography. The horse was euthanized because of progression of clinical signs. At necropsy, a mass was identified associated with the cerebellum, and histopathology was consistent with medulloblastoma, which has not been reported previously in the horse. |
| first_indexed | 2024-04-10T18:53:42Z |
| format | Article |
| id | doaj.art-7259f60a9d954b4893296de5156e541b |
| institution | Directory Open Access Journal |
| issn | 0891-6640 1939-1676 |
| language | English |
| last_indexed | 2024-04-10T18:53:42Z |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Veterinary Internal Medicine |
| spelling | doaj.art-7259f60a9d954b4893296de5156e541b2023-02-01T04:49:52ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762023-01-0137136136510.1111/jvim.16592Intracranial medulloblastoma as the cause of progressive ataxia in a 6‐month‐old draft horse cross geldingMegan Palmisano0Susan Bender1Amy L. Johnson2Department of Clinical Studies ‐ New Bolton Center University of Pennsylvania Kennett Square Pennsylvania USADepartment of Pathobiology University of Pennsylvania, Kennett Square Pennsylvania USADepartment of Clinical Studies ‐ New Bolton Center University of Pennsylvania Kennett Square Pennsylvania USAAbstract We describe the unique clinical presentation of a central nervous system neoplasm in a 6‐month‐old draft horse cross gelding. Based on the neurologic examination at admission, neurolocalization was most consistent with a mildly asymmetric cervical, multifocal, or diffuse myelopathy. Mild vestibular involvement also was considered, but no cranial nerve deficits were observed. The gelding was negative for Sarcocystis neurona or Neospora hughesi based on paired serum and cerebrospinal fluid (CSF) samples analyzed, with no evidence of cervical compression based on contrast myelography. The horse was euthanized because of progression of clinical signs. At necropsy, a mass was identified associated with the cerebellum, and histopathology was consistent with medulloblastoma, which has not been reported previously in the horse.https://doi.org/10.1111/jvim.16592ataxiabrainstemcerebellumequineintracranialneoplasia |
| spellingShingle | Megan Palmisano Susan Bender Amy L. Johnson Intracranial medulloblastoma as the cause of progressive ataxia in a 6‐month‐old draft horse cross gelding Journal of Veterinary Internal Medicine ataxia brainstem cerebellum equine intracranial neoplasia |
| title | Intracranial medulloblastoma as the cause of progressive ataxia in a 6‐month‐old draft horse cross gelding |
| title_full | Intracranial medulloblastoma as the cause of progressive ataxia in a 6‐month‐old draft horse cross gelding |
| title_fullStr | Intracranial medulloblastoma as the cause of progressive ataxia in a 6‐month‐old draft horse cross gelding |
| title_full_unstemmed | Intracranial medulloblastoma as the cause of progressive ataxia in a 6‐month‐old draft horse cross gelding |
| title_short | Intracranial medulloblastoma as the cause of progressive ataxia in a 6‐month‐old draft horse cross gelding |
| title_sort | intracranial medulloblastoma as the cause of progressive ataxia in a 6 month old draft horse cross gelding |
| topic | ataxia brainstem cerebellum equine intracranial neoplasia |
| url | https://doi.org/10.1111/jvim.16592 |
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