Multiple functions of protein phosphatases in receptor tyrosine kinase signaling revealed by interactome analysis

Multiple functions of protein phosphatases in receptor tyrosine kinase signaling revealed by interactome analysis

To obtain a global picture of how protein phosphatases are involved in receptor tyrosine kinase (RTK) signaling, we mapped the RTK-phosphatase interactome. Analyses of selected interactions revealed detailed mechanisms of their actions. This study provides new knowledge to better understand cancer d...

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Bibliographic Details
Main Authors: Zhong Yao, Igor Stagljar
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:Molecular & Cellular Oncology
Subjects:
dephosphorylation
mamth
myth
rtk
phosphorylation
protein-protein interaction
protein phosphatase
ptp
signaling
Online Access:http://dx.doi.org/10.1080/23723556.2017.1297101

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