Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

Retinitis Pigmentosa (RP) is a progressive, debilitating visual disorder caused by mutations in a diverse set of genes. In both humans with RP and mouse models of RP, rod photoreceptor dysfunction leads to loss of night vision, and is followed by secondary cone photoreceptor dysfunction and degenera...

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Bibliographic Details
Main Authors: Ryoji Amamoto, Grace K Wallick, Constance L Cepko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
retina
degeneration
cones
photoreceptor
retinitis pigmentosa
Online Access:https://elifesciences.org/articles/76389

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