A Case of α-Gal-Unrelated Red Meat-Induced Urticaria Treated by Omalizumab
A 70-year-old healthy woman was referred to our hospital for chronic urticaria. She did not have a history of allergy, asthma, and rhinitis. She was initially diagnosed with α-gal-related urticaria based on an episode of delayed-type urticaria after eating red meat. The results of the intracutaneous...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2021-09-01
|
| Series: | Case Reports in Dermatology |
| Subjects: | |
| Online Access: | https://www.karger.com/Article/FullText/518421 |
| _version_ | 1818887187804979200 |
|---|---|
| author | Makoto Kondo Yoshiaki Matsushima Shohei Iida Ai Umaoka Takehisa Nakanishi Koji Habe Keiichi Yamanaka |
| author_facet | Makoto Kondo Yoshiaki Matsushima Shohei Iida Ai Umaoka Takehisa Nakanishi Koji Habe Keiichi Yamanaka |
| author_sort | Makoto Kondo |
| collection | DOAJ |
| description | A 70-year-old healthy woman was referred to our hospital for chronic urticaria. She did not have a history of allergy, asthma, and rhinitis. She was initially diagnosed with α-gal-related urticaria based on an episode of delayed-type urticaria after eating red meat. The results of the intracutaneous allergen test for beef and pork were negative. Fluorenzyme immunoassays specific for IgE against α-gal, beef, and pork were also negative. She was diagnosed with an α-gal-unrelated red meat allergy following the reproduction of urticaria by a food challenge test. The patient was unresponsive to several drugs, including antihistamines or immunosuppressants. However, omalizumab administration suppressed her symptoms. Key Clinical Message: The diagnosis of red meat allergy may require a repeatability test by consuming red meat even though serum α-gal IgE antibody might be negative. The α-gal-unrelated red meat urticaria may be responsive to omalizumab. |
| first_indexed | 2024-12-19T16:33:15Z |
| format | Article |
| id | doaj.art-72614a51ec89466a8f73780779dd110b |
| institution | Directory Open Access Journal |
| issn | 1662-6567 |
| language | English |
| last_indexed | 2024-12-19T16:33:15Z |
| publishDate | 2021-09-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Dermatology |
| spelling | doaj.art-72614a51ec89466a8f73780779dd110b2022-12-21T20:14:04ZengKarger PublishersCase Reports in Dermatology1662-65672021-09-0113343744010.1159/000518421518421A Case of α-Gal-Unrelated Red Meat-Induced Urticaria Treated by OmalizumabMakoto KondoYoshiaki MatsushimaShohei IidaAi UmaokaTakehisa NakanishiKoji HabeKeiichi Yamanakahttps://orcid.org/0000-0003-3055-5202A 70-year-old healthy woman was referred to our hospital for chronic urticaria. She did not have a history of allergy, asthma, and rhinitis. She was initially diagnosed with α-gal-related urticaria based on an episode of delayed-type urticaria after eating red meat. The results of the intracutaneous allergen test for beef and pork were negative. Fluorenzyme immunoassays specific for IgE against α-gal, beef, and pork were also negative. She was diagnosed with an α-gal-unrelated red meat allergy following the reproduction of urticaria by a food challenge test. The patient was unresponsive to several drugs, including antihistamines or immunosuppressants. However, omalizumab administration suppressed her symptoms. Key Clinical Message: The diagnosis of red meat allergy may require a repeatability test by consuming red meat even though serum α-gal IgE antibody might be negative. The α-gal-unrelated red meat urticaria may be responsive to omalizumab.https://www.karger.com/Article/FullText/518421red meat-induced urticariaα-galigebeefporkomalizumab |
| spellingShingle | Makoto Kondo Yoshiaki Matsushima Shohei Iida Ai Umaoka Takehisa Nakanishi Koji Habe Keiichi Yamanaka A Case of α-Gal-Unrelated Red Meat-Induced Urticaria Treated by Omalizumab Case Reports in Dermatology red meat-induced urticaria α-gal ige beef pork omalizumab |
| title | A Case of α-Gal-Unrelated Red Meat-Induced Urticaria Treated by Omalizumab |
| title_full | A Case of α-Gal-Unrelated Red Meat-Induced Urticaria Treated by Omalizumab |
| title_fullStr | A Case of α-Gal-Unrelated Red Meat-Induced Urticaria Treated by Omalizumab |
| title_full_unstemmed | A Case of α-Gal-Unrelated Red Meat-Induced Urticaria Treated by Omalizumab |
| title_short | A Case of α-Gal-Unrelated Red Meat-Induced Urticaria Treated by Omalizumab |
| title_sort | case of α gal unrelated red meat induced urticaria treated by omalizumab |
| topic | red meat-induced urticaria α-gal ige beef pork omalizumab |
| url | https://www.karger.com/Article/FullText/518421 |
| work_keys_str_mv | AT makotokondo acaseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT yoshiakimatsushima acaseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT shoheiiida acaseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT aiumaoka acaseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT takehisanakanishi acaseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT kojihabe acaseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT keiichiyamanaka acaseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT makotokondo caseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT yoshiakimatsushima caseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT shoheiiida caseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT aiumaoka caseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT takehisanakanishi caseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT kojihabe caseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab AT keiichiyamanaka caseofagalunrelatedredmeatinducedurticariatreatedbyomalizumab |