Identification of genes with high heterogeneity of expression as a predictor of different prognosis and therapeutic responses in colorectal cancer: a challenge and a strategy

Identification of genes with high heterogeneity of expression as a predictor of different prognosis and therapeutic responses in colorectal cancer: a challenge and a strategy

Abstract Background Molecular heterogeneity is one of the most important concerns in colorectal cancer (CRC), which results in a wide range of therapy responses and patient prognosis. We aimed to identify the genes with high heterogeneity of expression (HHE) and their relation with prognosis and dru...

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Bibliographic Details
Main Authors: Ebrahim Salehitabar, Mohammad Mahdevar, Ali Valipour Motlagh, Farzad Seyed Forootan, Sara Feizbakhshan, Dina Zohrabi, Maryam Peymani
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cancer Cell International
Subjects:
High heterogeneity
Tumor sample
Mutation
Gene expression
Cancer treatment
Online Access:https://doi.org/10.1186/s12935-022-02694-9

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