Florid cystitis glandularis (intestinal type) with mucus extravasation: Two case reports and literature review

BackgroundCystitis glandularis is a common bladder epithelial lesion characterized by hyperplasia and metaplasia of the bladder mucosa epithelium. The pathogenesis of cystitis glandularis of the intestinal type is unknown and less common. When cystitis glandularis (intestinal type) is extremely seve...

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Main Authors: Tao Zhang, Si-Fan Yin, Wen-Bo Feng, Chang-Xing Ke
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Surgery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2023.1048119/full
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author Tao Zhang
Si-Fan Yin
Wen-Bo Feng
Chang-Xing Ke
author_facet Tao Zhang
Si-Fan Yin
Wen-Bo Feng
Chang-Xing Ke
author_sort Tao Zhang
collection DOAJ
description BackgroundCystitis glandularis is a common bladder epithelial lesion characterized by hyperplasia and metaplasia of the bladder mucosa epithelium. The pathogenesis of cystitis glandularis of the intestinal type is unknown and less common. When cystitis glandularis (intestinal type) is extremely severely differentiated, it is called florid cystitis glandularis (the occurrence is extremely rare).Case summaryBoth patients were middle-aged men. In patient 1, the lesion was also seen in the posterior wall and was diagnosed more than 1 year ago as cystitis glandularis with urethral stricture. Patient 2 was examined for symptoms such as hematuria and was found to have an occupied bladder; both were treated surgically, and the postoperative pathology was diagnosed as florid cystitis glandularis (intestinal type), with mucus extravasation.ConclusionThe pathogenesis of cystitis glandularis (intestinal type) is unknown and less common. When cystitis glandularis of the intestinal type is extremely severely differentiated, we call it florid cystitis glandularis. It is more common in the bladder neck and trigone. The clinical manifestations are mainly symptoms of bladder irritation, or hematuria as the main complaint, which rarely leads to hydronephrosis. Imaging is nonspecific and the diagnosis depends on pathology. Surgical excision of the lesion is possible. Due to the malignant potential of cystitis glandularis of intestinal type, postoperative follow-up is required.
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spelling doaj.art-72657e142e25467e9b66b0e46b38a71c2023-02-24T05:26:46ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-02-011010.3389/fsurg.2023.10481191048119Florid cystitis glandularis (intestinal type) with mucus extravasation: Two case reports and literature reviewTao ZhangSi-Fan YinWen-Bo FengChang-Xing KeBackgroundCystitis glandularis is a common bladder epithelial lesion characterized by hyperplasia and metaplasia of the bladder mucosa epithelium. The pathogenesis of cystitis glandularis of the intestinal type is unknown and less common. When cystitis glandularis (intestinal type) is extremely severely differentiated, it is called florid cystitis glandularis (the occurrence is extremely rare).Case summaryBoth patients were middle-aged men. In patient 1, the lesion was also seen in the posterior wall and was diagnosed more than 1 year ago as cystitis glandularis with urethral stricture. Patient 2 was examined for symptoms such as hematuria and was found to have an occupied bladder; both were treated surgically, and the postoperative pathology was diagnosed as florid cystitis glandularis (intestinal type), with mucus extravasation.ConclusionThe pathogenesis of cystitis glandularis (intestinal type) is unknown and less common. When cystitis glandularis of the intestinal type is extremely severely differentiated, we call it florid cystitis glandularis. It is more common in the bladder neck and trigone. The clinical manifestations are mainly symptoms of bladder irritation, or hematuria as the main complaint, which rarely leads to hydronephrosis. Imaging is nonspecific and the diagnosis depends on pathology. Surgical excision of the lesion is possible. Due to the malignant potential of cystitis glandularis of intestinal type, postoperative follow-up is required.https://www.frontiersin.org/articles/10.3389/fsurg.2023.1048119/fullcystitis glandularisintestinal typediagnosistreatmentclinical features
spellingShingle Tao Zhang
Si-Fan Yin
Wen-Bo Feng
Chang-Xing Ke
Florid cystitis glandularis (intestinal type) with mucus extravasation: Two case reports and literature review
Frontiers in Surgery
cystitis glandularis
intestinal type
diagnosis
treatment
clinical features
title Florid cystitis glandularis (intestinal type) with mucus extravasation: Two case reports and literature review
title_full Florid cystitis glandularis (intestinal type) with mucus extravasation: Two case reports and literature review
title_fullStr Florid cystitis glandularis (intestinal type) with mucus extravasation: Two case reports and literature review
title_full_unstemmed Florid cystitis glandularis (intestinal type) with mucus extravasation: Two case reports and literature review
title_short Florid cystitis glandularis (intestinal type) with mucus extravasation: Two case reports and literature review
title_sort florid cystitis glandularis intestinal type with mucus extravasation two case reports and literature review
topic cystitis glandularis
intestinal type
diagnosis
treatment
clinical features
url https://www.frontiersin.org/articles/10.3389/fsurg.2023.1048119/full
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AT wenbofeng floridcystitisglandularisintestinaltypewithmucusextravasationtwocasereportsandliteraturereview
AT changxingke floridcystitisglandularisintestinaltypewithmucusextravasationtwocasereportsandliteraturereview