PD-L2 Blockade Exacerbates Liver Lesion in Mice Infected with <i>Capillaria hepatica</i> through Reducing Alternatively Activated Macrophages

PD-L2 Blockade Exacerbates Liver Lesion in Mice Infected with <i>Capillaria hepatica</i> through Reducing Alternatively Activated Macrophages

<i>Capillaria hepatica</i> is a seriously neglected zoonotic parasite, which infects the liver of mammalian hosts, causing fibrosis or even hepatic failure. At present, the immune responses elicited by <i>C. hepatica</i> are not fully understood, and the role(s) of the progra...

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Bibliographic Details
Main Authors: Minjun Huang, Xiaoli Li, Xiaoyan Zheng, Fei Wang, Yang Zou, Lei Wang
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Tropical Medicine and Infectious Disease
Subjects:
alternatively activated macrophages
<i>Capillaria hepatica</i>
immunomodulation
programmed death ligand 2
Online Access:https://www.mdpi.com/2414-6366/8/1/46

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