Mast Cells in Cardiac Fibrosis: New Insights Suggest Opportunities for Intervention

Mast Cells in Cardiac Fibrosis: New Insights Suggest Opportunities for Intervention

Mast cells (MC) are innate immune cells present in virtually all body tissues with key roles in allergic disease and host defense. MCs recognize damage-associated molecular patterns (DAMPs) through expression of multiple receptors including Toll-like receptors and the IL-33 receptor ST2. MCs can be...

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Bibliographic Details
Main Authors: Stephanie A. Legere, Ian D. Haidl, Jean-François Légaré, Jean S. Marshall
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
mast cell
cardiac fibrosis
inflammation
tissue remodeling
immunology
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00580/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00580/full

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