Chemoresistant Gestational Trophoblastic Neoplasia: A Case Report

Gestational trophoblastic neoplasia (GTN) is a disease of women in reproductive age. It is one of the most chemotherapy responsive and highly curable cancer. It is diagnosed when there is clinical, radiologic, pathologic, and/or hormonal evidence of persistent or relapsed gestational trophoblastic...

Full description

Bibliographic Details
Main Authors: SUDHA CP, SAHANA M
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2014-07-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/4645/8274_CE(Ra1)_F(H)_PF1(PAK)_PFA(AK)_PF2(AGAK)_PF2(PN).pdf
_version_ 1818108941990625280
author SUDHA CP
SAHANA M
author_facet SUDHA CP
SAHANA M
author_sort SUDHA CP
collection DOAJ
description Gestational trophoblastic neoplasia (GTN) is a disease of women in reproductive age. It is one of the most chemotherapy responsive and highly curable cancer. It is diagnosed when there is clinical, radiologic, pathologic, and/or hormonal evidence of persistent or relapsed gestational trophoblastic disease. In most instances, it is cured by surgical evacuation of the uterus. If persistent, it is treated with chemotherapy which provides response in >90% of the cases. In the unresponsive persistent cases and if the women has completed her child bearing, hysterectomy is generally recommended. Here, we report a rare case of chemoresistant GTN which was confirmed to be placental-site trophoblastic tumour (PSTT) on biopsy.
first_indexed 2024-12-11T02:23:22Z
format Article
id doaj.art-726fc6f7c6084fcaaaa9011fe21ea34f
institution Directory Open Access Journal
issn 2249-782X
0973-709X
language English
last_indexed 2024-12-11T02:23:22Z
publishDate 2014-07-01
publisher JCDR Research and Publications Private Limited
record_format Article
series Journal of Clinical and Diagnostic Research
spelling doaj.art-726fc6f7c6084fcaaaa9011fe21ea34f2022-12-22T01:24:00ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-07-0187OD12OD1310.7860/JCDR/2014/8274.4645Chemoresistant Gestational Trophoblastic Neoplasia: A Case ReportSUDHA CP0SAHANA M1Associate Professor, Department of Obstetrics and Gynaecology, Kempegowda Institute of Medical sciences, Bangalore, India.Post Graduate, Department of Obstetrics and Gynaecology, Kempegowda Institute of Medical sciences, Bangalore, India.Gestational trophoblastic neoplasia (GTN) is a disease of women in reproductive age. It is one of the most chemotherapy responsive and highly curable cancer. It is diagnosed when there is clinical, radiologic, pathologic, and/or hormonal evidence of persistent or relapsed gestational trophoblastic disease. In most instances, it is cured by surgical evacuation of the uterus. If persistent, it is treated with chemotherapy which provides response in >90% of the cases. In the unresponsive persistent cases and if the women has completed her child bearing, hysterectomy is generally recommended. Here, we report a rare case of chemoresistant GTN which was confirmed to be placental-site trophoblastic tumour (PSTT) on biopsy.https://jcdr.net/articles/PDF/4645/8274_CE(Ra1)_F(H)_PF1(PAK)_PFA(AK)_PF2(AGAK)_PF2(PN).pdfgtnplacental site trophoblastic tumouruterine tumour
spellingShingle SUDHA CP
SAHANA M
Chemoresistant Gestational Trophoblastic Neoplasia: A Case Report
Journal of Clinical and Diagnostic Research
gtn
placental site trophoblastic tumour
uterine tumour
title Chemoresistant Gestational Trophoblastic Neoplasia: A Case Report
title_full Chemoresistant Gestational Trophoblastic Neoplasia: A Case Report
title_fullStr Chemoresistant Gestational Trophoblastic Neoplasia: A Case Report
title_full_unstemmed Chemoresistant Gestational Trophoblastic Neoplasia: A Case Report
title_short Chemoresistant Gestational Trophoblastic Neoplasia: A Case Report
title_sort chemoresistant gestational trophoblastic neoplasia a case report
topic gtn
placental site trophoblastic tumour
uterine tumour
url https://jcdr.net/articles/PDF/4645/8274_CE(Ra1)_F(H)_PF1(PAK)_PFA(AK)_PF2(AGAK)_PF2(PN).pdf
work_keys_str_mv AT sudhacp chemoresistantgestationaltrophoblasticneoplasiaacasereport
AT sahanam chemoresistantgestationaltrophoblasticneoplasiaacasereport