Babam2 Regulates Cell Cycle Progression and Pluripotency in Mouse Embryonic Stem Cells as Revealed by Induced DNA Damage
BRISC and BRCA1-A complex member 2 (<i>Babam2</i>) plays an essential role in promoting cell cycle progression and preventing cellular senescence. <i>Babam2</i>-deficient fibroblasts show proliferation defect and premature senescence compared with their wild-type (WT) counter...
Main Authors: | Cheuk Yiu Tenny Chung, Paulisally Hau Yi Lo, Kenneth Ka Ho Lee |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/8/10/397 |
Similar Items
-
MOUSE AND HUMAN EMBRYONIC STEM CELLS
by: A. G. Menzorov
Published: (2014-12-01) -
The Role of E3s in Regulating Pluripotency of Embryonic Stem Cells and Induced Pluripotent Stem Cells
by: Yahong Wu, et al.
Published: (2021-01-01) -
The mTOR Pathway in Pluripotent Stem Cells: Lessons for Understanding Cancer Cell Dormancy
by: Bashar A. Alhasan, et al.
Published: (2021-11-01) -
EGFR deficiency leads to impaired self-renewal and pluripotency of mouse embryonic stem cells
by: Miaoying Yu, et al.
Published: (2019-01-01) -
A Genome-Wide CRISPR Screen Identifies Factors Regulating Pluripotency Exit in Mouse Embryonic Stem Cells
by: Chen Gao, et al.
Published: (2022-07-01)