Radioprotective effects of melanin-glucan complex from Fomes Fomentarius and indralin at irradiation of mice BALB/C by dose of 5,95 Gy/8,5 min

Protective effect of melanin-glucan complex from F. fomentarius (MGC) and Russian armed forces radiopro-tector indralin in the model of acute exposure by dose of 5.95 Gy/8.5min care is compared. Obtained results indi-cate availabi¬lity at MGC and indralin both direct and indirect "bystander eff...

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Main Authors: O. F. Seniuk, V. O. Kovalev, L. A. Palamar, N. I. Krul, L. F. Gorovoj, V. M. Shevel
Format: Article
Language:English
Published: Institute for Nuclear Research, National Academy of Sciences of Ukraine 2014-06-01
Series:Âderna Fìzika ta Energetika
Subjects:
Online Access:http://jnpae.kinr.kiev.ua/15.2/Articles_PDF/jnpae-2014-15-0178-Seniuk.pdf
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author O. F. Seniuk
V. O. Kovalev
L. A. Palamar
N. I. Krul
L. F. Gorovoj
V. M. Shevel
author_facet O. F. Seniuk
V. O. Kovalev
L. A. Palamar
N. I. Krul
L. F. Gorovoj
V. M. Shevel
author_sort O. F. Seniuk
collection DOAJ
description Protective effect of melanin-glucan complex from F. fomentarius (MGC) and Russian armed forces radiopro-tector indralin in the model of acute exposure by dose of 5.95 Gy/8.5min care is compared. Obtained results indi-cate availabi¬lity at MGC and indralin both direct and indirect "bystander effect” of DNA-protective properties, as well as severe anxiolytic activity. Thus for indralin protection factor was 0.33 when in MGC it was 2.3 times higher (0.75).
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spelling doaj.art-7272763d00474aca8bc5943cb342ff872022-12-22T03:39:33ZengInstitute for Nuclear Research, National Academy of Sciences of UkraineÂderna Fìzika ta Energetika1818-331X2074-05652014-06-01152178188Radioprotective effects of melanin-glucan complex from Fomes Fomentarius and indralin at irradiation of mice BALB/C by dose of 5,95 Gy/8,5 minO. F. Seniuk0V. O. Kovalev1 L. A. Palamar2 N. I. Krul3L. F. Gorovoj4V. M. Shevel5Institute for Safety Problems of NPP, National Academy of Sciences of Ukraine, Chornobyl, UkraineInstitute for Safety Problems of NPP, National Academy of Sciences of Ukraine, Chornobyl, UkraineInstitute for Safety Problems of NPP, National Academy of Sciences of Ukraine, Chornobyl, UkraineInstitute of Cell Biology and Genetic Engineering, National Academy of Sciences of Ukraine, KyivInstitute of Cell Biology and Genetic Engineering, National Academy of Sciences of Ukraine, KyivInstitute for Nuclear Research, National Academy of Sciences of UkraineProtective effect of melanin-glucan complex from F. fomentarius (MGC) and Russian armed forces radiopro-tector indralin in the model of acute exposure by dose of 5.95 Gy/8.5min care is compared. Obtained results indi-cate availabi¬lity at MGC and indralin both direct and indirect "bystander effect” of DNA-protective properties, as well as severe anxiolytic activity. Thus for indralin protection factor was 0.33 when in MGC it was 2.3 times higher (0.75).http://jnpae.kinr.kiev.ua/15.2/Articles_PDF/jnpae-2014-15-0178-Seniuk.pdfionizing radiationacute exposureprotection coefficientDNA single-strand breaksmushroom biopo-lymersindralin"bystander effect"behavioral responses
spellingShingle O. F. Seniuk
V. O. Kovalev
L. A. Palamar
N. I. Krul
L. F. Gorovoj
V. M. Shevel
Radioprotective effects of melanin-glucan complex from Fomes Fomentarius and indralin at irradiation of mice BALB/C by dose of 5,95 Gy/8,5 min
Âderna Fìzika ta Energetika
ionizing radiation
acute exposure
protection coefficient
DNA single-strand breaks
mushroom biopo-lymers
indralin
"bystander effect"
behavioral responses
title Radioprotective effects of melanin-glucan complex from Fomes Fomentarius and indralin at irradiation of mice BALB/C by dose of 5,95 Gy/8,5 min
title_full Radioprotective effects of melanin-glucan complex from Fomes Fomentarius and indralin at irradiation of mice BALB/C by dose of 5,95 Gy/8,5 min
title_fullStr Radioprotective effects of melanin-glucan complex from Fomes Fomentarius and indralin at irradiation of mice BALB/C by dose of 5,95 Gy/8,5 min
title_full_unstemmed Radioprotective effects of melanin-glucan complex from Fomes Fomentarius and indralin at irradiation of mice BALB/C by dose of 5,95 Gy/8,5 min
title_short Radioprotective effects of melanin-glucan complex from Fomes Fomentarius and indralin at irradiation of mice BALB/C by dose of 5,95 Gy/8,5 min
title_sort radioprotective effects of melanin glucan complex from fomes fomentarius and indralin at irradiation of mice balb c by dose of 5 95 gy 8 5 min
topic ionizing radiation
acute exposure
protection coefficient
DNA single-strand breaks
mushroom biopo-lymers
indralin
"bystander effect"
behavioral responses
url http://jnpae.kinr.kiev.ua/15.2/Articles_PDF/jnpae-2014-15-0178-Seniuk.pdf
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