Efficacy and safety of hydroxychloroquine as pre-and post-exposure prophylaxis and treatment of COVID-19: A systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trials.

Efficacy and safety of hydroxychloroquine as pre-and post-exposure prophylaxis and treatment of COVID-19: A systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trials.

ABSTRACT: Background: Hydroxychloroquine (HCQ) is an anti-malarial and immunomodulatory drug considered a potential candidate for drug repurposing in COVID-19 due to their in vitro antiviral activity against SARS-CoV-2. Despite the potential antiviral effects and anti-inflammatory profile, the resu...

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Bibliographic Details
Main Authors: Paulo Ricardo Martins-Filho, PhD, Lis Campos Ferreira, MD, MSc, Luana Heimfarth, PhD, Adriano Antunes de Souza Araújo, PhD, Lucindo José Quintans-Júnior, PhD
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:The Lancet Regional Health. Americas
Subjects:
Hydroxychloroquine
COVID-19
SARS-CoV-2
Online Access:http://www.sciencedirect.com/science/article/pii/S2667193X21000582

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