Multiplex immunohistochemistry defines two cholesterol metabolism patterns predicting immunotherapeutic outcomes in gastric cancer

Multiplex immunohistochemistry defines two cholesterol metabolism patterns predicting immunotherapeutic outcomes in gastric cancer

Abstract Background The role of cholesterol metabolism in gastric cancer (GC) and its implications for tumor characteristics and immunotherapy response remain poorly understood. In this study, our aim was to investigate this role, identify associated metabolic subtypes, and assess their clinical imp...

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Bibliographic Details
Main Authors: Wei Tang, Guanghua Li, Qi Lin, Zhenzhen Zhu, Zhao Wang, Zhixiong Wang
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Translational Medicine
Subjects:
Gastric cancer
Cholesterol metabolism
Metabolic subtypes
Immunotherapy
Prognostic signature
Biomarkers
Online Access:https://doi.org/10.1186/s12967-023-04758-4

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