Long non-coding RNA Gm37494 alleviates osteoarthritis chondrocyte injury via the microRNA-181a-5p/GABRA1 axis

Long non-coding RNA Gm37494 alleviates osteoarthritis chondrocyte injury via the microRNA-181a-5p/GABRA1 axis

Abstract Objective This study was conducted to investigate the effect of long non-coding RNA (lncRNA) Gm37494 on osteoarthritis (OA) and its related molecular mechanism. Methods The cartilage tissues were obtained from OA patients, and an OA mouse model was induced by the destabilization of the medi...

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Bibliographic Details
Main Authors: Aidong Yuan, Penghuan Wu, Zhinian Zhong, Zhengyan He, Wenhu Li
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteoarthritis
Long non-coding RNA Gm37494
microRNA-181a-5p
GABRA1
Chondrocyte
Inflammation
Online Access:https://doi.org/10.1186/s13018-022-03202-5

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