Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex
There is limited evidence on the effects of age and sex on intrinsic connectivity of networks underlying cognition during childhood and adolescence. Independent component analysis was conducted in 113 subjects aged 7–18; the default mode, executive control, anterior salience, basal ganglia, language...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2016-02-01
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| Series: | Developmental Cognitive Neuroscience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878929315300670 |
| _version_ | 1819038380351029248 |
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| author | Cristina Solé-Padullés Josefina Castro-Fornieles Elena de la Serna Rosa Calvo Inmaculada Baeza Jaime Moya Luisa Lázaro Mireia Rosa Nuria Bargalló Gisela Sugranyes |
| author_facet | Cristina Solé-Padullés Josefina Castro-Fornieles Elena de la Serna Rosa Calvo Inmaculada Baeza Jaime Moya Luisa Lázaro Mireia Rosa Nuria Bargalló Gisela Sugranyes |
| author_sort | Cristina Solé-Padullés |
| collection | DOAJ |
| description | There is limited evidence on the effects of age and sex on intrinsic connectivity of networks underlying cognition during childhood and adolescence. Independent component analysis was conducted in 113 subjects aged 7–18; the default mode, executive control, anterior salience, basal ganglia, language and visuospatial networks were identified. The effect of age was examined with multiple regression, while sex and ‘age × sex’ interactions were assessed by dividing the sample according to age (7–12 and 13–18 years). As age increased, connectivity in the dorsal and ventral default mode network became more anterior and posterior, respectively, while in the executive control network, connectivity increased within frontoparietal regions. The basal ganglia network showed increased engagement of striatum, thalami and precuneus. The anterior salience network showed greater connectivity in frontal areas and anterior cingulate, and less connectivity of orbitofrontal, middle cingulate and temporoparietal regions. The language network presented increased connectivity of inferior frontal and decreased connectivity within the right middle frontal and left inferior parietal cortices. The visuospatial network showed greater engagement of inferior parietal and frontal cortices. No effect of sex, nor age by sex interactions was observed. These findings provide evidence of strengthening of cortico-cortical and cortico-subcortical networks across childhood and adolescence. |
| first_indexed | 2024-12-21T08:36:23Z |
| format | Article |
| id | doaj.art-72868c1d42934ac081f66ddaa9371b60 |
| institution | Directory Open Access Journal |
| issn | 1878-9293 1878-9307 |
| language | English |
| last_indexed | 2024-12-21T08:36:23Z |
| publishDate | 2016-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Developmental Cognitive Neuroscience |
| spelling | doaj.art-72868c1d42934ac081f66ddaa9371b602022-12-21T19:10:03ZengElsevierDevelopmental Cognitive Neuroscience1878-92931878-93072016-02-0117C354410.1016/j.dcn.2015.11.004Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sexCristina Solé-Padullés0Josefina Castro-Fornieles1Elena de la Serna2Rosa Calvo3Inmaculada Baeza4Jaime Moya5Luisa Lázaro6Mireia Rosa7Nuria Bargalló8Gisela Sugranyes9August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Rosselló 149-153, Barcelona 08036, SpainAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), Rosselló 149-153, Barcelona 08036, SpainBiomedical Research Networking Centre Consortium (CIBERSAM), Monforte de lemos 3-5, Madrid 28029, SpainAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), Rosselló 149-153, Barcelona 08036, SpainAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), Rosselló 149-153, Barcelona 08036, SpainAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), Rosselló 149-153, Barcelona 08036, SpainAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), Rosselló 149-153, Barcelona 08036, SpainDepartment of Child and Adolescent Psychiatry and Psychology, SGR1119, Institute of Neuroscience, Hospital Clínic of Barcelona, Villarroel 170, Barcelona 08036, SpainBiomedical Research Networking Centre Consortium (CIBERSAM), Monforte de lemos 3-5, Madrid 28029, SpainAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), Rosselló 149-153, Barcelona 08036, SpainThere is limited evidence on the effects of age and sex on intrinsic connectivity of networks underlying cognition during childhood and adolescence. Independent component analysis was conducted in 113 subjects aged 7–18; the default mode, executive control, anterior salience, basal ganglia, language and visuospatial networks were identified. The effect of age was examined with multiple regression, while sex and ‘age × sex’ interactions were assessed by dividing the sample according to age (7–12 and 13–18 years). As age increased, connectivity in the dorsal and ventral default mode network became more anterior and posterior, respectively, while in the executive control network, connectivity increased within frontoparietal regions. The basal ganglia network showed increased engagement of striatum, thalami and precuneus. The anterior salience network showed greater connectivity in frontal areas and anterior cingulate, and less connectivity of orbitofrontal, middle cingulate and temporoparietal regions. The language network presented increased connectivity of inferior frontal and decreased connectivity within the right middle frontal and left inferior parietal cortices. The visuospatial network showed greater engagement of inferior parietal and frontal cortices. No effect of sex, nor age by sex interactions was observed. These findings provide evidence of strengthening of cortico-cortical and cortico-subcortical networks across childhood and adolescence.http://www.sciencedirect.com/science/article/pii/S1878929315300670Functional magnetic resonance imaging (fMRI)Resting-state networks (RSN)DevelopmentIndependent component analysis (ICA) |
| spellingShingle | Cristina Solé-Padullés Josefina Castro-Fornieles Elena de la Serna Rosa Calvo Inmaculada Baeza Jaime Moya Luisa Lázaro Mireia Rosa Nuria Bargalló Gisela Sugranyes Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex Developmental Cognitive Neuroscience Functional magnetic resonance imaging (fMRI) Resting-state networks (RSN) Development Independent component analysis (ICA) |
| title | Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex |
| title_full | Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex |
| title_fullStr | Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex |
| title_full_unstemmed | Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex |
| title_short | Intrinsic connectivity networks from childhood to late adolescence: Effects of age and sex |
| title_sort | intrinsic connectivity networks from childhood to late adolescence effects of age and sex |
| topic | Functional magnetic resonance imaging (fMRI) Resting-state networks (RSN) Development Independent component analysis (ICA) |
| url | http://www.sciencedirect.com/science/article/pii/S1878929315300670 |
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