D-dimer level elevation can aid in detection of asymptomatic COVID-19 presenting with acute cerebral infarction
Coronavirus disease 2019 (COVID-19) mainly manifests as a respiratory syndrome, besides causing other complications. Severe COVID-19 may also present with coagulopathy, leading to venous thrombosis and cerebral infarction. Generally, acute stroke is a secondary complication in patients displaying re...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-03-01
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| Series: | eNeurologicalSci |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405650220300733 |
| _version_ | 1819053825507459072 |
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| author | Takeru Umemura Hirohisa Kondo Hirotsugu Ohta Koichiro Futatsuya Takamitsu Mizobe Junkoh Yamamoto |
| author_facet | Takeru Umemura Hirohisa Kondo Hirotsugu Ohta Koichiro Futatsuya Takamitsu Mizobe Junkoh Yamamoto |
| author_sort | Takeru Umemura |
| collection | DOAJ |
| description | Coronavirus disease 2019 (COVID-19) mainly manifests as a respiratory syndrome, besides causing other complications. Severe COVID-19 may also present with coagulopathy, leading to venous thrombosis and cerebral infarction. Generally, acute stroke is a secondary complication in patients displaying respiratory syndromes. Here, we present a case of acute stroke in an 84-year-old female patient who did not manifest any respiratory symptoms. The patient had no cough or fever before the stroke onset; nevertheless, COVID-19 PCR test was positive. The patient also had markedly elevated serum D-dimer levels. Our findings suggest that coagulopathy can occur even in a patient with asymptomatic COVID-19 infection, and to our knowledge, this is the first report of such a case. We concluded that elevated D-dimer levels can serve as an additional COVID-19 screening tool in stroke patients. |
| first_indexed | 2024-12-21T12:41:53Z |
| format | Article |
| id | doaj.art-72897fd8dbb247bb99fee8db21c82600 |
| institution | Directory Open Access Journal |
| issn | 2405-6502 |
| language | English |
| last_indexed | 2024-12-21T12:41:53Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | eNeurologicalSci |
| spelling | doaj.art-72897fd8dbb247bb99fee8db21c826002022-12-21T19:03:45ZengElseviereNeurologicalSci2405-65022021-03-0122100294D-dimer level elevation can aid in detection of asymptomatic COVID-19 presenting with acute cerebral infarctionTakeru Umemura0Hirohisa Kondo1Hirotsugu Ohta2Koichiro Futatsuya3Takamitsu Mizobe4Junkoh Yamamoto5Department of Neurosurgery, Kyushu Rosai Hospital, Moji Medical Center, Japan; Corresponding author at: Department of Neurosurgery, Kyushu Rosai Hospital, Moji Medical Center, 3-1 Higashiminatomachi, Moji-ku, Kitakyushu City, Fukuoka 801-8502, Japan.Department of Neurosurgery, Kyushu Rosai Hospital, Moji Medical Center, JapanDepartment of Neurosurgery, Kyushu Rosai Hospital, Moji Medical Center, JapanDepartment of Radiology, Kyushu Rosai Hospital, Moji Medical Center, JapanDepartment of Hematology, Kyushu Rosai Hospital, Moji Medical Center, JapanDepartment of Neurosurgery, University of Occupational and Environmental Health, JapanCoronavirus disease 2019 (COVID-19) mainly manifests as a respiratory syndrome, besides causing other complications. Severe COVID-19 may also present with coagulopathy, leading to venous thrombosis and cerebral infarction. Generally, acute stroke is a secondary complication in patients displaying respiratory syndromes. Here, we present a case of acute stroke in an 84-year-old female patient who did not manifest any respiratory symptoms. The patient had no cough or fever before the stroke onset; nevertheless, COVID-19 PCR test was positive. The patient also had markedly elevated serum D-dimer levels. Our findings suggest that coagulopathy can occur even in a patient with asymptomatic COVID-19 infection, and to our knowledge, this is the first report of such a case. We concluded that elevated D-dimer levels can serve as an additional COVID-19 screening tool in stroke patients.http://www.sciencedirect.com/science/article/pii/S2405650220300733COVID-19Cerebral infarctionChest CTPCRD-dimer |
| spellingShingle | Takeru Umemura Hirohisa Kondo Hirotsugu Ohta Koichiro Futatsuya Takamitsu Mizobe Junkoh Yamamoto D-dimer level elevation can aid in detection of asymptomatic COVID-19 presenting with acute cerebral infarction eNeurologicalSci COVID-19 Cerebral infarction Chest CT PCR D-dimer |
| title | D-dimer level elevation can aid in detection of asymptomatic COVID-19 presenting with acute cerebral infarction |
| title_full | D-dimer level elevation can aid in detection of asymptomatic COVID-19 presenting with acute cerebral infarction |
| title_fullStr | D-dimer level elevation can aid in detection of asymptomatic COVID-19 presenting with acute cerebral infarction |
| title_full_unstemmed | D-dimer level elevation can aid in detection of asymptomatic COVID-19 presenting with acute cerebral infarction |
| title_short | D-dimer level elevation can aid in detection of asymptomatic COVID-19 presenting with acute cerebral infarction |
| title_sort | d dimer level elevation can aid in detection of asymptomatic covid 19 presenting with acute cerebral infarction |
| topic | COVID-19 Cerebral infarction Chest CT PCR D-dimer |
| url | http://www.sciencedirect.com/science/article/pii/S2405650220300733 |
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