Clinical Experience of Sirolimus Regarding Efficacy and Safety in Systemic Lupus Erythematosus

New treatment options constitute unmet needs for patients diagnosed with systemic lupus erythematosus (SLE). Inhibition of the mammalian target of rapamycin (mTOR) pathway by sirolimus, a drug approved and in clinical use to prevent transplant rejection, has shown promising effects in lupus animal m...

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מידע ביבליוגרפי
Main Authors: Per Eriksson, Philip Wallin, Christopher Sjöwall
פורמט: Article
שפה:English
יצא לאור: Frontiers Media S.A. 2019-02-01
סדרה:Frontiers in Pharmacology
נושאים:
גישה מקוונת:https://www.frontiersin.org/article/10.3389/fphar.2019.00082/full