The direct use of enzymatic biofuel cells as functional bioelectronics

Enzymatic biofuel cells (EBFCs) are a subgroup of fuel cells that use enzymes as catalysts. EBFCs that utilize physiological substrates such as glucose or lactate are of great interest as implantable or wearable power sources to activate medical devices. This contribution introduces the working prin...

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Main Author: Xinxin Xiao
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2022-01-01
Series:eScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667141721000525
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author Xinxin Xiao
author_facet Xinxin Xiao
author_sort Xinxin Xiao
collection DOAJ
description Enzymatic biofuel cells (EBFCs) are a subgroup of fuel cells that use enzymes as catalysts. EBFCs that utilize physiological substrates such as glucose or lactate are of great interest as implantable or wearable power sources to activate medical devices. This contribution introduces the working principles of EBFCs and summarizes recent progress in EBFC-enabled biosensors, pulse generators, and therapy. Biosensors with self-powered characteristic enjoy high selectivity, leading to potential “instrument-free” or “expensive-instrument-free” measurement. Autonomous pulse generation is based on the hybrid of EBFC and supercapacitor, which is promising for the application in medical related electrostimulation. By providing the direct electrical stimulation, or controllably releasing drug, EBFCs can also be used for self-powered therapeutic system. The further combination of self-powered sensing and treating enables EBFC as a possible platform of diagnostics and therapeutics. Future efforts can be focused on resolving the limited power density and lifetime of EBFC.
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spelling doaj.art-728ef56da0444c449408fb1c921724b22022-12-22T03:01:50ZengKeAi Communications Co. Ltd.eScience2667-14172022-01-012119The direct use of enzymatic biofuel cells as functional bioelectronicsXinxin Xiao0Corresponding author.; Department of Chemistry, Technical University of Denmark, 2800, Kongens Lyngby, DenmarkEnzymatic biofuel cells (EBFCs) are a subgroup of fuel cells that use enzymes as catalysts. EBFCs that utilize physiological substrates such as glucose or lactate are of great interest as implantable or wearable power sources to activate medical devices. This contribution introduces the working principles of EBFCs and summarizes recent progress in EBFC-enabled biosensors, pulse generators, and therapy. Biosensors with self-powered characteristic enjoy high selectivity, leading to potential “instrument-free” or “expensive-instrument-free” measurement. Autonomous pulse generation is based on the hybrid of EBFC and supercapacitor, which is promising for the application in medical related electrostimulation. By providing the direct electrical stimulation, or controllably releasing drug, EBFCs can also be used for self-powered therapeutic system. The further combination of self-powered sensing and treating enables EBFC as a possible platform of diagnostics and therapeutics. Future efforts can be focused on resolving the limited power density and lifetime of EBFC.http://www.sciencedirect.com/science/article/pii/S2667141721000525Enzymatic biofuel cellSelf-poweredBioelectronicSensorDrug release
spellingShingle Xinxin Xiao
The direct use of enzymatic biofuel cells as functional bioelectronics
eScience
Enzymatic biofuel cell
Self-powered
Bioelectronic
Sensor
Drug release
title The direct use of enzymatic biofuel cells as functional bioelectronics
title_full The direct use of enzymatic biofuel cells as functional bioelectronics
title_fullStr The direct use of enzymatic biofuel cells as functional bioelectronics
title_full_unstemmed The direct use of enzymatic biofuel cells as functional bioelectronics
title_short The direct use of enzymatic biofuel cells as functional bioelectronics
title_sort direct use of enzymatic biofuel cells as functional bioelectronics
topic Enzymatic biofuel cell
Self-powered
Bioelectronic
Sensor
Drug release
url http://www.sciencedirect.com/science/article/pii/S2667141721000525
work_keys_str_mv AT xinxinxiao thedirectuseofenzymaticbiofuelcellsasfunctionalbioelectronics
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