Acute liver failure due to herpes simplex viral hepatitis diagnosed by skin lesions and blood tests: a case report
Abstract Background The incidence of acute liver failure from herpes simplex virus is rare. Case presentation A 71-year-old Japanese man was diagnosed with acute liver failure and was transferred to our hospital. Steroid therapy, plasma exchange, and hemodiafiltration were started for liver failure,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-08-01
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| Series: | Journal of Medical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13256-023-04083-w |
| _version_ | 1797743992052383744 |
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| author | Kento Shionoya Makoto Kako Sakue Masuda Makomo Makazu Kazuya Koizumi |
| author_facet | Kento Shionoya Makoto Kako Sakue Masuda Makomo Makazu Kazuya Koizumi |
| author_sort | Kento Shionoya |
| collection | DOAJ |
| description | Abstract Background The incidence of acute liver failure from herpes simplex virus is rare. Case presentation A 71-year-old Japanese man was diagnosed with acute liver failure and was transferred to our hospital. Steroid therapy, plasma exchange, and hemodiafiltration were started for liver failure, and antimicrobial therapy was initiated for pneumonia. Staphylococcus epidermidis was detected in blood culture. Skin rash appeared; a positive anti-herpes simplex virus result led to the diagnosis of acute liver failure from herpes simplex virus. Hence, acyclovir was started. After blood tests improved, treatments for acute liver failure were discontinued. Antimicrobial therapy was continued; however, he died. In this case, persistent bacteremia and drug-induced liver damage due to acyclovir may have contributed to his death. Conclusions Acute liver failure can lead to complications and death. Thus, careful observation is crucial, even if the patient has shown some improvements. |
| first_indexed | 2024-03-12T15:03:27Z |
| format | Article |
| id | doaj.art-7294eee6bc1a41be882247c8c1db6e59 |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-03-12T15:03:27Z |
| publishDate | 2023-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-7294eee6bc1a41be882247c8c1db6e592023-08-13T11:13:57ZengBMCJournal of Medical Case Reports1752-19472023-08-011711510.1186/s13256-023-04083-wAcute liver failure due to herpes simplex viral hepatitis diagnosed by skin lesions and blood tests: a case reportKento Shionoya0Makoto Kako1Sakue Masuda2Makomo Makazu3Kazuya Koizumi4Shonan Gastroenterology Medicine Center, Shonan Kamakura General HospitalShonan Gastroenterology Medicine Center, Shonan Kamakura General HospitalShonan Gastroenterology Medicine Center, Shonan Kamakura General HospitalShonan Gastroenterology Medicine Center, Shonan Kamakura General HospitalShonan Gastroenterology Medicine Center, Shonan Kamakura General HospitalAbstract Background The incidence of acute liver failure from herpes simplex virus is rare. Case presentation A 71-year-old Japanese man was diagnosed with acute liver failure and was transferred to our hospital. Steroid therapy, plasma exchange, and hemodiafiltration were started for liver failure, and antimicrobial therapy was initiated for pneumonia. Staphylococcus epidermidis was detected in blood culture. Skin rash appeared; a positive anti-herpes simplex virus result led to the diagnosis of acute liver failure from herpes simplex virus. Hence, acyclovir was started. After blood tests improved, treatments for acute liver failure were discontinued. Antimicrobial therapy was continued; however, he died. In this case, persistent bacteremia and drug-induced liver damage due to acyclovir may have contributed to his death. Conclusions Acute liver failure can lead to complications and death. Thus, careful observation is crucial, even if the patient has shown some improvements.https://doi.org/10.1186/s13256-023-04083-wHerpes simplex viral hepatitisAcute liver failureAcyclovirPlasma exchangeHemodiafiltrationCase report |
| spellingShingle | Kento Shionoya Makoto Kako Sakue Masuda Makomo Makazu Kazuya Koizumi Acute liver failure due to herpes simplex viral hepatitis diagnosed by skin lesions and blood tests: a case report Journal of Medical Case Reports Herpes simplex viral hepatitis Acute liver failure Acyclovir Plasma exchange Hemodiafiltration Case report |
| title | Acute liver failure due to herpes simplex viral hepatitis diagnosed by skin lesions and blood tests: a case report |
| title_full | Acute liver failure due to herpes simplex viral hepatitis diagnosed by skin lesions and blood tests: a case report |
| title_fullStr | Acute liver failure due to herpes simplex viral hepatitis diagnosed by skin lesions and blood tests: a case report |
| title_full_unstemmed | Acute liver failure due to herpes simplex viral hepatitis diagnosed by skin lesions and blood tests: a case report |
| title_short | Acute liver failure due to herpes simplex viral hepatitis diagnosed by skin lesions and blood tests: a case report |
| title_sort | acute liver failure due to herpes simplex viral hepatitis diagnosed by skin lesions and blood tests a case report |
| topic | Herpes simplex viral hepatitis Acute liver failure Acyclovir Plasma exchange Hemodiafiltration Case report |
| url | https://doi.org/10.1186/s13256-023-04083-w |
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