Individual differences in chemotherapy-induced anticipatory nausea
Anticipatory Nausea (AN) is a severe side effect of chemotherapy that can lead cancer patients to discontinue their treatment. This kind of nausea is usually elicited by the re-exposure of the patients to the clinical context they need to attend to be treated. There has been considerable agreement t...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2013-08-01
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Series: | Frontiers in Psychology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpsyg.2013.00502/full |
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author | Marcial eRodríguez |
author_facet | Marcial eRodríguez |
author_sort | Marcial eRodríguez |
collection | DOAJ |
description | Anticipatory Nausea (AN) is a severe side effect of chemotherapy that can lead cancer patients to discontinue their treatment. This kind of nausea is usually elicited by the re-exposure of the patients to the clinical context they need to attend to be treated. There has been considerable agreement that AN represents a paradigmatic example of Pavlovian conditioning, and within this framework, several behavioral interventions have been proposed in order to prevent this psychopathology. However, some studies have questioned the validity of the Pavlovian approach, suggesting that CS-US associations are neither necessary nor sufficient for AN to occur. The data and the alternative theories behind such criticisms are discussed. Additionally, it is suggested that animal models of AN could be enriched by taking into account rats’ individual differences. |
first_indexed | 2024-12-14T15:49:39Z |
format | Article |
id | doaj.art-729d13440c7743a6987eb1e29fddedac |
institution | Directory Open Access Journal |
issn | 1664-1078 |
language | English |
last_indexed | 2024-12-14T15:49:39Z |
publishDate | 2013-08-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Psychology |
spelling | doaj.art-729d13440c7743a6987eb1e29fddedac2022-12-21T22:55:24ZengFrontiers Media S.A.Frontiers in Psychology1664-10782013-08-01410.3389/fpsyg.2013.0050242880Individual differences in chemotherapy-induced anticipatory nauseaMarcial eRodríguez0University of GranadaAnticipatory Nausea (AN) is a severe side effect of chemotherapy that can lead cancer patients to discontinue their treatment. This kind of nausea is usually elicited by the re-exposure of the patients to the clinical context they need to attend to be treated. There has been considerable agreement that AN represents a paradigmatic example of Pavlovian conditioning, and within this framework, several behavioral interventions have been proposed in order to prevent this psychopathology. However, some studies have questioned the validity of the Pavlovian approach, suggesting that CS-US associations are neither necessary nor sufficient for AN to occur. The data and the alternative theories behind such criticisms are discussed. Additionally, it is suggested that animal models of AN could be enriched by taking into account rats’ individual differences.http://journal.frontiersin.org/Journal/10.3389/fpsyg.2013.00502/fullNauseaPersonalityRatschemotherapyClassical Conditioningdifferences |
spellingShingle | Marcial eRodríguez Individual differences in chemotherapy-induced anticipatory nausea Frontiers in Psychology Nausea Personality Rats chemotherapy Classical Conditioning differences |
title | Individual differences in chemotherapy-induced anticipatory nausea |
title_full | Individual differences in chemotherapy-induced anticipatory nausea |
title_fullStr | Individual differences in chemotherapy-induced anticipatory nausea |
title_full_unstemmed | Individual differences in chemotherapy-induced anticipatory nausea |
title_short | Individual differences in chemotherapy-induced anticipatory nausea |
title_sort | individual differences in chemotherapy induced anticipatory nausea |
topic | Nausea Personality Rats chemotherapy Classical Conditioning differences |
url | http://journal.frontiersin.org/Journal/10.3389/fpsyg.2013.00502/full |
work_keys_str_mv | AT marcialerodriguez individualdifferencesinchemotherapyinducedanticipatorynausea |