Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus

Chronic kidney disease (CKD) is a general concept that involves renal tissue regardless of the aetiology of the leading disease. CKD occurs in one out of every two patients with diabetes mellitus (DM) and appreciably limits the duration and quality of life. CKD can be diagnosed by glomerular filtrat...

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Main Authors: Tatiana N. Markova, Viktoriia V. Sadovskaya, Marina Y. Bespyatova
Format: Article
Language:English
Published: Endocrinology Research Centre 2017-12-01
Series:Сахарный диабет
Subjects:
Online Access:https://www.dia-endojournals.ru/jour/article/view/9268
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author Tatiana N. Markova
Viktoriia V. Sadovskaya
Marina Y. Bespyatova
author_facet Tatiana N. Markova
Viktoriia V. Sadovskaya
Marina Y. Bespyatova
author_sort Tatiana N. Markova
collection DOAJ
description Chronic kidney disease (CKD) is a general concept that involves renal tissue regardless of the aetiology of the leading disease. CKD occurs in one out of every two patients with diabetes mellitus (DM) and appreciably limits the duration and quality of life. CKD can be diagnosed by glomerular filtration rate (GFR), which is recognised as the most representative indicator of the quantity and total workload of nephrons. However, the decrease in GFR occurs at an advanced stage of nephropathy and causes irreversible renal damage, which ultimately requires substitutive renal therapy and, thereby, increases the expense. In this regard, clinical trials have been conducted to identify the biomarkers of CKD reflecting renal damage at earlier stages of the disease. This article presents an overview of modern methods for the diagnosis of CKD and preclinical markers of kidney injury in patients with DM.
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spelling doaj.art-729ec10b979e4bb6a3c7e18314d31e5d2024-03-20T11:48:01ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782017-12-0120645446010.14341/DM92688378Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitusTatiana N. Markova0Viktoriia V. Sadovskaya1Marina Y. Bespyatova2<p>Municipal clinical hospital №52;&nbsp;Moscow State University of Medicine and Dentistry named after A.I. Evdokimov</p><p>Moscow State University of Medicine and Dentistry named after A.I. Evdokimov</p><p>City polyclinic № 115</p>Chronic kidney disease (CKD) is a general concept that involves renal tissue regardless of the aetiology of the leading disease. CKD occurs in one out of every two patients with diabetes mellitus (DM) and appreciably limits the duration and quality of life. CKD can be diagnosed by glomerular filtration rate (GFR), which is recognised as the most representative indicator of the quantity and total workload of nephrons. However, the decrease in GFR occurs at an advanced stage of nephropathy and causes irreversible renal damage, which ultimately requires substitutive renal therapy and, thereby, increases the expense. In this regard, clinical trials have been conducted to identify the biomarkers of CKD reflecting renal damage at earlier stages of the disease. This article presents an overview of modern methods for the diagnosis of CKD and preclinical markers of kidney injury in patients with DM.https://www.dia-endojournals.ru/jour/article/view/9268diabetes mellitusdiabetic nephropathiesbiomarkersglomerular filtration rate
spellingShingle Tatiana N. Markova
Viktoriia V. Sadovskaya
Marina Y. Bespyatova
Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
Сахарный диабет
diabetes mellitus
diabetic nephropathies
biomarkers
glomerular filtration rate
title Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
title_full Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
title_fullStr Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
title_full_unstemmed Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
title_short Modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
title_sort modern methods of diagnosing chronic kidney disease in patients with diabetes mellitus
topic diabetes mellitus
diabetic nephropathies
biomarkers
glomerular filtration rate
url https://www.dia-endojournals.ru/jour/article/view/9268
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