The relationship between depression and benign prostatic hyperplasia in middle-aged and elderly men in India: a large-scale population study
Abstract Background There have been few investigations on the association between depression and benign prostatic hyperplasia (BPH). This study aims to explore the correlation between depression and BPH among middle-aged and older men in India. Methods We utilized data from male individuals aged 45 ...
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| Format: | Article |
| Language: | English |
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BMC
2023-11-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-023-17027-2 |
| _version_ | 1797636620881494016 |
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| author | Xiaoyang Liu Kai Ma Luchen Yang Zhufeng Peng Pan Song Zhenghuan Liu Jing Zhou Yunfei Yu Qiang Dong |
| author_facet | Xiaoyang Liu Kai Ma Luchen Yang Zhufeng Peng Pan Song Zhenghuan Liu Jing Zhou Yunfei Yu Qiang Dong |
| author_sort | Xiaoyang Liu |
| collection | DOAJ |
| description | Abstract Background There have been few investigations on the association between depression and benign prostatic hyperplasia (BPH). This study aims to explore the correlation between depression and BPH among middle-aged and older men in India. Methods We utilized data from male individuals aged 45 years and older who participated in the initial wave (2017–2018) of the Longitudinal Aging Study in India (LASI). The presence of BPH symptoms was based on self-reported information, while depressive symptoms were evaluated using CESD-10. The analysis was a cross-sectional study conducted on a final sample size of 30,108 male participants. To examine associations, we employed multivariate logistic regression analysis along with subgroup analysis and interaction tests. Results A total of 439 (1.46%) men reported BPH and had a higher depression score (10.18 ± 4.22 vs. 9.28 ± 4.00). The findings indicated a significant association between the depression score and the likelihood of developing BPH, even after accounting for all potential confounding variables (OR = 1.054, 95% CI: 1.030–1.078, p < 0.00001). The participants were then categorized into a depression group and a normal group based on their CESD-10 score, using a threshold of 10 to ascertain the existence or nonexistence of depression. After adjusting for all variables in model IV, the findings continued to exhibit statistical significance (OR = 1.611, CI: 1.327–1.955, p < 0.00001). Significant interaction effects of age, education level, caste or tribe, and alcohol consumption were observed (p for interaction < 0.05). Conclusion Our research found that BPH was significantly linked to the presence of depressive symptoms among middle-aged and elderly Indian men. Additional prospective research is necessary to clarify this association and investigate potential mechanisms. |
| first_indexed | 2024-03-11T12:37:42Z |
| format | Article |
| id | doaj.art-72a850e800fc41f58f7591ea33de63cd |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-03-11T12:37:42Z |
| publishDate | 2023-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-72a850e800fc41f58f7591ea33de63cd2023-11-05T12:31:21ZengBMCBMC Public Health1471-24582023-11-012311910.1186/s12889-023-17027-2The relationship between depression and benign prostatic hyperplasia in middle-aged and elderly men in India: a large-scale population studyXiaoyang Liu0Kai Ma1Luchen Yang2Zhufeng Peng3Pan Song4Zhenghuan Liu5Jing Zhou6Yunfei Yu7Qiang Dong8Department of Urology, Institute of Urology, West China Hospital, Sichuan UniversityDepartment of Urology, Institute of Urology, West China Hospital, Sichuan UniversityDepartment of Urology, Institute of Urology, West China Hospital, Sichuan UniversityDepartment of Urology, Institute of Urology, West China Hospital, Sichuan UniversityDepartment of Urology, Institute of Urology, West China Hospital, Sichuan UniversityDepartment of Urology, Institute of Urology, West China Hospital, Sichuan UniversityDepartment of Urology, Institute of Urology, West China Hospital, Sichuan UniversityDepartment of Urology, Institute of Urology, West China Hospital, Sichuan UniversityDepartment of Urology, Institute of Urology, West China Hospital, Sichuan UniversityAbstract Background There have been few investigations on the association between depression and benign prostatic hyperplasia (BPH). This study aims to explore the correlation between depression and BPH among middle-aged and older men in India. Methods We utilized data from male individuals aged 45 years and older who participated in the initial wave (2017–2018) of the Longitudinal Aging Study in India (LASI). The presence of BPH symptoms was based on self-reported information, while depressive symptoms were evaluated using CESD-10. The analysis was a cross-sectional study conducted on a final sample size of 30,108 male participants. To examine associations, we employed multivariate logistic regression analysis along with subgroup analysis and interaction tests. Results A total of 439 (1.46%) men reported BPH and had a higher depression score (10.18 ± 4.22 vs. 9.28 ± 4.00). The findings indicated a significant association between the depression score and the likelihood of developing BPH, even after accounting for all potential confounding variables (OR = 1.054, 95% CI: 1.030–1.078, p < 0.00001). The participants were then categorized into a depression group and a normal group based on their CESD-10 score, using a threshold of 10 to ascertain the existence or nonexistence of depression. After adjusting for all variables in model IV, the findings continued to exhibit statistical significance (OR = 1.611, CI: 1.327–1.955, p < 0.00001). Significant interaction effects of age, education level, caste or tribe, and alcohol consumption were observed (p for interaction < 0.05). Conclusion Our research found that BPH was significantly linked to the presence of depressive symptoms among middle-aged and elderly Indian men. Additional prospective research is necessary to clarify this association and investigate potential mechanisms.https://doi.org/10.1186/s12889-023-17027-2Benign prostatic hyperplasiaDepressionElderlyLASIRisk factors |
| spellingShingle | Xiaoyang Liu Kai Ma Luchen Yang Zhufeng Peng Pan Song Zhenghuan Liu Jing Zhou Yunfei Yu Qiang Dong The relationship between depression and benign prostatic hyperplasia in middle-aged and elderly men in India: a large-scale population study BMC Public Health Benign prostatic hyperplasia Depression Elderly LASI Risk factors |
| title | The relationship between depression and benign prostatic hyperplasia in middle-aged and elderly men in India: a large-scale population study |
| title_full | The relationship between depression and benign prostatic hyperplasia in middle-aged and elderly men in India: a large-scale population study |
| title_fullStr | The relationship between depression and benign prostatic hyperplasia in middle-aged and elderly men in India: a large-scale population study |
| title_full_unstemmed | The relationship between depression and benign prostatic hyperplasia in middle-aged and elderly men in India: a large-scale population study |
| title_short | The relationship between depression and benign prostatic hyperplasia in middle-aged and elderly men in India: a large-scale population study |
| title_sort | relationship between depression and benign prostatic hyperplasia in middle aged and elderly men in india a large scale population study |
| topic | Benign prostatic hyperplasia Depression Elderly LASI Risk factors |
| url | https://doi.org/10.1186/s12889-023-17027-2 |
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