Blastocyst Transplantation Strategies in Women of Different Ages
(1) Background: Single blastocyst transfers (SBT) and double blastocyst transfers (DBT) are widely used in clinical practice. The objective of this study was to investigate the application of these two strategies in women of different ages. (2) Methods: Analysis was carried out on 5477 frozen embryo...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-02-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/12/4/1618 |
| _version_ | 1797620131368534016 |
|---|---|
| author | Dandan Yang Menghan Chai Ni Yang Han Yang Xingxing Wen Jing Wang Yongqi Fan Yunxia Cao Zhiguo Zhang Beili Chen |
| author_facet | Dandan Yang Menghan Chai Ni Yang Han Yang Xingxing Wen Jing Wang Yongqi Fan Yunxia Cao Zhiguo Zhang Beili Chen |
| author_sort | Dandan Yang |
| collection | DOAJ |
| description | (1) Background: Single blastocyst transfers (SBT) and double blastocyst transfers (DBT) are widely used in clinical practice. The objective of this study was to investigate the application of these two strategies in women of different ages. (2) Methods: Analysis was carried out on 5477 frozen embryo transfer cycles of women in different ages. All the cycles were divided into three groups according to the age of the included women: <35, 35–39, and >39. The live birth rate (LBR) and multiple birth rate (MBR) between the SBT and DBT among these groups, respectively, were compared. (3) Results: In the women < 35 group, the LBR was similar in SBT and DBT, but the MBR was higher in DBT than SBT. In women 35–39, with >10 oocytes retrieved, the MBR in DBT was significantly higher than SBT, but there was no significant difference in LBR between the two groups; with ≤10 oocytes retrieved, the LBR in DBT were significantly higher than SBT, but the MBT was not significantly different between the two groups. In women > 39, the LBR and MBR were lower in the SBT than DBT, but the differences were not statistically significant. (4) Conclusions: Selective SET is appropriate for most young women, whereas older women are advised to make individualized choices based on the number of oocytes retrieved and blastocyst quality. |
| first_indexed | 2024-03-11T08:37:41Z |
| format | Article |
| id | doaj.art-72ab40d2766a4cb4af341822b263eae0 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T08:37:41Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-72ab40d2766a4cb4af341822b263eae02023-11-16T21:22:06ZengMDPI AGJournal of Clinical Medicine2077-03832023-02-01124161810.3390/jcm12041618Blastocyst Transplantation Strategies in Women of Different AgesDandan Yang0Menghan Chai1Ni Yang2Han Yang3Xingxing Wen4Jing Wang5Yongqi Fan6Yunxia Cao7Zhiguo Zhang8Beili Chen9Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No. 81 Meishan Road, Hefei 230032, ChinaReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No. 81 Meishan Road, Hefei 230032, ChinaReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No. 81 Meishan Road, Hefei 230032, ChinaDepartment of Biomedical Engineering, Anhui Medical University, No. 81 Meishan Road, Hefei 230032, ChinaReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No. 81 Meishan Road, Hefei 230032, ChinaReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No. 81 Meishan Road, Hefei 230032, ChinaReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No. 81 Meishan Road, Hefei 230032, ChinaReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No. 81 Meishan Road, Hefei 230032, ChinaReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No. 81 Meishan Road, Hefei 230032, ChinaReproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No. 81 Meishan Road, Hefei 230032, China(1) Background: Single blastocyst transfers (SBT) and double blastocyst transfers (DBT) are widely used in clinical practice. The objective of this study was to investigate the application of these two strategies in women of different ages. (2) Methods: Analysis was carried out on 5477 frozen embryo transfer cycles of women in different ages. All the cycles were divided into three groups according to the age of the included women: <35, 35–39, and >39. The live birth rate (LBR) and multiple birth rate (MBR) between the SBT and DBT among these groups, respectively, were compared. (3) Results: In the women < 35 group, the LBR was similar in SBT and DBT, but the MBR was higher in DBT than SBT. In women 35–39, with >10 oocytes retrieved, the MBR in DBT was significantly higher than SBT, but there was no significant difference in LBR between the two groups; with ≤10 oocytes retrieved, the LBR in DBT were significantly higher than SBT, but the MBT was not significantly different between the two groups. In women > 39, the LBR and MBR were lower in the SBT than DBT, but the differences were not statistically significant. (4) Conclusions: Selective SET is appropriate for most young women, whereas older women are advised to make individualized choices based on the number of oocytes retrieved and blastocyst quality.https://www.mdpi.com/2077-0383/12/4/1618single blastocyst transferdouble blastocyst transferlive birth ratemultiple birth ratepreterm birth rate |
| spellingShingle | Dandan Yang Menghan Chai Ni Yang Han Yang Xingxing Wen Jing Wang Yongqi Fan Yunxia Cao Zhiguo Zhang Beili Chen Blastocyst Transplantation Strategies in Women of Different Ages Journal of Clinical Medicine single blastocyst transfer double blastocyst transfer live birth rate multiple birth rate preterm birth rate |
| title | Blastocyst Transplantation Strategies in Women of Different Ages |
| title_full | Blastocyst Transplantation Strategies in Women of Different Ages |
| title_fullStr | Blastocyst Transplantation Strategies in Women of Different Ages |
| title_full_unstemmed | Blastocyst Transplantation Strategies in Women of Different Ages |
| title_short | Blastocyst Transplantation Strategies in Women of Different Ages |
| title_sort | blastocyst transplantation strategies in women of different ages |
| topic | single blastocyst transfer double blastocyst transfer live birth rate multiple birth rate preterm birth rate |
| url | https://www.mdpi.com/2077-0383/12/4/1618 |
| work_keys_str_mv | AT dandanyang blastocysttransplantationstrategiesinwomenofdifferentages AT menghanchai blastocysttransplantationstrategiesinwomenofdifferentages AT niyang blastocysttransplantationstrategiesinwomenofdifferentages AT hanyang blastocysttransplantationstrategiesinwomenofdifferentages AT xingxingwen blastocysttransplantationstrategiesinwomenofdifferentages AT jingwang blastocysttransplantationstrategiesinwomenofdifferentages AT yongqifan blastocysttransplantationstrategiesinwomenofdifferentages AT yunxiacao blastocysttransplantationstrategiesinwomenofdifferentages AT zhiguozhang blastocysttransplantationstrategiesinwomenofdifferentages AT beilichen blastocysttransplantationstrategiesinwomenofdifferentages |