Antiproliferative Effect of Androgen Receptor Inhibition in Mesenchymal Stem-Like Triple-Negative Breast Cancer

Antiproliferative Effect of Androgen Receptor Inhibition in Mesenchymal Stem-Like Triple-Negative Breast Cancer

Background/Aims: Androgen receptor (AR), a steroid hormone receptor, has recently emerged as prognostic and treatment-predictive marker in breast cancer. Previous studies have shown that AR is widely expressed in up to one-third of triple-negative breast cancer (TNBC). However, the role of AR in TNB...

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Bibliographic Details
Main Authors: Aiyu Zhu, Yan Li, Wei Song, Yumei Xu, Fang Yang, Wenwen Zhang, Yongmei Yin, Xiaoxiang Guan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Androgen receptor
Triple-negative breast cancer
p53
p73
p21
Online Access:http://www.karger.com/Article/FullText/443052

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