Effect of Foot-and-Mouth Disease Virus 2B Viroporin on Expression and Extraction of Mammalian Cell Culture Produced Foot-and-Mouth Disease Virus-like Particles

Effect of Foot-and-Mouth Disease Virus 2B Viroporin on Expression and Extraction of Mammalian Cell Culture Produced Foot-and-Mouth Disease Virus-like Particles

To improve the production of foot-and-mouth disease (FMD) molecular vaccines, we sought to understand the effects of the FMD virus (FMDV) 2B viroporin in an experimental, plasmid-based, virus-like particle (VLP) vaccine. Inclusion of the FMDV viroporin 2B into the human Adenovirus 5 vectored FMD vac...

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Bibliographic Details
Main Authors: Victoria Primavera, Janine Simmons, Benjamin A. Clark, John G. Neilan, Michael Puckette
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Vaccines
Subjects:
FMDV
virus-like particle
vaccine
2B
viroporin
3C
Online Access:https://www.mdpi.com/2076-393X/10/9/1506

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