Insufficient anti-spike RBD IgA responses after triple vaccination with intramuscular mRNA BNT162b2 vaccine against SARS-CoV-2

Insufficient anti-spike RBD IgA responses after triple vaccination with intramuscular mRNA BNT162b2 vaccine against SARS-CoV-2

Objectives: This study aims to examine whether the parenterally administered mRNA-based COVID-19 vaccines can induce sufficient mucosal-type IgA responses to prevent SARS-CoV-2 transmission. Methods: We examined the longitudinal kinetics of SARS-CoV-2 spike RBD-specific IgA and IgG responses in sera...

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Bibliographic Details
Main Authors: Michinobu Yoshimura, Atsuhiko Sakamoto, Ryo Ozuru, Yusuke Kurihara, Ryota Itoh, Kazunari Ishii, Akinori Shimizu, Bin Chou, Yusuke Sechi, Aya Fujikane, Shigeki Nabeshima, Kenji Hiromatsu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
SARS-CoV-2
BNT162b2
Breakthrough infection
IgA
mRNA vaccination
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023108036

Internet

http://www.sciencedirect.com/science/article/pii/S2405844023108036

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