The Short Overview on the Relevance of Fatty Acids for Human Cardiovascular Disorders
This review presents existing evidence of the influence of saturated and unsaturated fatty acids on cardiovascular diseases (CVD). Data are discussed regarding the roles of the most relevant fatty acids, such as myristic (C14:0), palmitic (C16:0), stearic (C18:0), palmitoleic (C16:1), oleic (C18:1),...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-07-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/10/8/1127 |
| _version_ | 1797560858361987072 |
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| author | Viktoriya S. Shramko Yana V. Polonskaya Elena V. Kashtanova Ekaterina M. Stakhneva Yuliya I. Ragino |
| author_facet | Viktoriya S. Shramko Yana V. Polonskaya Elena V. Kashtanova Ekaterina M. Stakhneva Yuliya I. Ragino |
| author_sort | Viktoriya S. Shramko |
| collection | DOAJ |
| description | This review presents existing evidence of the influence of saturated and unsaturated fatty acids on cardiovascular diseases (CVD). Data are discussed regarding the roles of the most relevant fatty acids, such as myristic (C14:0), palmitic (C16:0), stearic (C18:0), palmitoleic (C16:1), oleic (C18:1), linoleic (C18:2), <i>α</i>-linolenic (C18:3, <i>ω</i>-3), <i>γ</i>-linolenic (C18:3, <i>ω</i>-6), arachidonic (C20:4), eicosapentaenoic (C20:5), docosahexaenoic (C22:6), and docosapentaenoic (C22:5) acid. The accumulated knowledge has expanded the understanding of the involvement of fatty acids in metabolic processes, thereby enabling the transition from basic exploratory studies to practical issues of application of these biomolecules to CVD treatment. In the future, these findings are expected to facilitate the interpretation and prognosis of changes in metabolic lipid aberrations in CVD. |
| first_indexed | 2024-03-10T18:06:10Z |
| format | Article |
| id | doaj.art-72b48ff3129d49819c42674662e4d9aa |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-10T18:06:10Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-72b48ff3129d49819c42674662e4d9aa2023-11-20T08:28:42ZengMDPI AGBiomolecules2218-273X2020-07-01108112710.3390/biom10081127The Short Overview on the Relevance of Fatty Acids for Human Cardiovascular DisordersViktoriya S. Shramko0Yana V. Polonskaya1Elena V. Kashtanova2Ekaterina M. Stakhneva3Yuliya I. Ragino4Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, 630089 Novosibirsk, RussiaBranch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, 630089 Novosibirsk, RussiaBranch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, 630089 Novosibirsk, RussiaBranch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, 630089 Novosibirsk, RussiaBranch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, 630089 Novosibirsk, RussiaThis review presents existing evidence of the influence of saturated and unsaturated fatty acids on cardiovascular diseases (CVD). Data are discussed regarding the roles of the most relevant fatty acids, such as myristic (C14:0), palmitic (C16:0), stearic (C18:0), palmitoleic (C16:1), oleic (C18:1), linoleic (C18:2), <i>α</i>-linolenic (C18:3, <i>ω</i>-3), <i>γ</i>-linolenic (C18:3, <i>ω</i>-6), arachidonic (C20:4), eicosapentaenoic (C20:5), docosahexaenoic (C22:6), and docosapentaenoic (C22:5) acid. The accumulated knowledge has expanded the understanding of the involvement of fatty acids in metabolic processes, thereby enabling the transition from basic exploratory studies to practical issues of application of these biomolecules to CVD treatment. In the future, these findings are expected to facilitate the interpretation and prognosis of changes in metabolic lipid aberrations in CVD.https://www.mdpi.com/2218-273X/10/8/1127saturated fatty acidmonounsaturated fatty acidpolyunsaturated fatty acidcardiovascular diseaseblood lipid profile |
| spellingShingle | Viktoriya S. Shramko Yana V. Polonskaya Elena V. Kashtanova Ekaterina M. Stakhneva Yuliya I. Ragino The Short Overview on the Relevance of Fatty Acids for Human Cardiovascular Disorders Biomolecules saturated fatty acid monounsaturated fatty acid polyunsaturated fatty acid cardiovascular disease blood lipid profile |
| title | The Short Overview on the Relevance of Fatty Acids for Human Cardiovascular Disorders |
| title_full | The Short Overview on the Relevance of Fatty Acids for Human Cardiovascular Disorders |
| title_fullStr | The Short Overview on the Relevance of Fatty Acids for Human Cardiovascular Disorders |
| title_full_unstemmed | The Short Overview on the Relevance of Fatty Acids for Human Cardiovascular Disorders |
| title_short | The Short Overview on the Relevance of Fatty Acids for Human Cardiovascular Disorders |
| title_sort | short overview on the relevance of fatty acids for human cardiovascular disorders |
| topic | saturated fatty acid monounsaturated fatty acid polyunsaturated fatty acid cardiovascular disease blood lipid profile |
| url | https://www.mdpi.com/2218-273X/10/8/1127 |
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