Synthesis, characterization and application of spherical and uniform molecularly imprinted polymeric nanobeads as efficient sorbent for selective extraction of rosmarinic acid from plant matrix
This work reports the synthesis and application of uniform and spherical molecularly imprinted polymeric (MIP) nanobeads for selective and efficient preconcentration of Rosmarinic acid (RA). The as-prepared RA MIP nanobeads were characterized using Fourier transform infrared spectroscopy (FTIR), sca...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-05-01
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| Series: | Journal of Materials Research and Technology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2238785421003653 |
| _version_ | 1819096719067971584 |
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| author | Sara Alipour Parviz Aberoomand Azar Syed Waqif Husain Hamid Reza Rajabi |
| author_facet | Sara Alipour Parviz Aberoomand Azar Syed Waqif Husain Hamid Reza Rajabi |
| author_sort | Sara Alipour |
| collection | DOAJ |
| description | This work reports the synthesis and application of uniform and spherical molecularly imprinted polymeric (MIP) nanobeads for selective and efficient preconcentration of Rosmarinic acid (RA). The as-prepared RA MIP nanobeads were characterized using Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and Brunauer–Emmett–Teller (BET) techniques. As analyzed, nano-sized particles of MIP with spherical and uniform shape and the average size of 88 nm were synthesized. The prepared MIP nanobeads were used in an ultrasonic-assisted dispersive solid phase extraction approach (UA-DSPE) for extraction of RA as a natural antioxidant specie from the extract of Salvia Officinalis leaves. In UA-DSPE process, the RA content of the samples was determined using high-performance liquid chromatography (HPLC). The highest recovery percentage (>90%) was observed after loading of RA solution (pH 5.7) and after elution with 3 mL of acetic acid aqueous solution, followed by 6 min sonication. The selectivity studies demonstrated a selective and high affinity binding of the template molecule (i.e. RA) toward MIP sorbent compared to other compounds such as gallic acid, caffeic acid, and pyrocatechol. |
| first_indexed | 2024-12-22T00:03:40Z |
| format | Article |
| id | doaj.art-72b53a74885747c9ab3f5672575e4bcd |
| institution | Directory Open Access Journal |
| issn | 2238-7854 |
| language | English |
| last_indexed | 2024-12-22T00:03:40Z |
| publishDate | 2021-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Materials Research and Technology |
| spelling | doaj.art-72b53a74885747c9ab3f5672575e4bcd2022-12-21T18:45:38ZengElsevierJournal of Materials Research and Technology2238-78542021-05-011222982306Synthesis, characterization and application of spherical and uniform molecularly imprinted polymeric nanobeads as efficient sorbent for selective extraction of rosmarinic acid from plant matrixSara Alipour0Parviz Aberoomand Azar1Syed Waqif Husain2Hamid Reza Rajabi3Department of Analytical Chemistry, Faculty of Basic Science, Science and Research Branch, Islamic Azad University, Tehran, IranDepartment of Analytical Chemistry, Faculty of Basic Science, Science and Research Branch, Islamic Azad University, Tehran, Iran; Corresponding author.Department of Analytical Chemistry, Faculty of Basic Science, Science and Research Branch, Islamic Azad University, Tehran, IranChemistry Department, Yasouj University, Yasouj, 75918-74831, Iran; Corresponding author.This work reports the synthesis and application of uniform and spherical molecularly imprinted polymeric (MIP) nanobeads for selective and efficient preconcentration of Rosmarinic acid (RA). The as-prepared RA MIP nanobeads were characterized using Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and Brunauer–Emmett–Teller (BET) techniques. As analyzed, nano-sized particles of MIP with spherical and uniform shape and the average size of 88 nm were synthesized. The prepared MIP nanobeads were used in an ultrasonic-assisted dispersive solid phase extraction approach (UA-DSPE) for extraction of RA as a natural antioxidant specie from the extract of Salvia Officinalis leaves. In UA-DSPE process, the RA content of the samples was determined using high-performance liquid chromatography (HPLC). The highest recovery percentage (>90%) was observed after loading of RA solution (pH 5.7) and after elution with 3 mL of acetic acid aqueous solution, followed by 6 min sonication. The selectivity studies demonstrated a selective and high affinity binding of the template molecule (i.e. RA) toward MIP sorbent compared to other compounds such as gallic acid, caffeic acid, and pyrocatechol.http://www.sciencedirect.com/science/article/pii/S2238785421003653High-performance liquid chromatographyMolecularly imprinted polymeric nanobeadsRosmarinic acidSalvia officinalisUltrasonic |
| spellingShingle | Sara Alipour Parviz Aberoomand Azar Syed Waqif Husain Hamid Reza Rajabi Synthesis, characterization and application of spherical and uniform molecularly imprinted polymeric nanobeads as efficient sorbent for selective extraction of rosmarinic acid from plant matrix Journal of Materials Research and Technology High-performance liquid chromatography Molecularly imprinted polymeric nanobeads Rosmarinic acid Salvia officinalis Ultrasonic |
| title | Synthesis, characterization and application of spherical and uniform molecularly imprinted polymeric nanobeads as efficient sorbent for selective extraction of rosmarinic acid from plant matrix |
| title_full | Synthesis, characterization and application of spherical and uniform molecularly imprinted polymeric nanobeads as efficient sorbent for selective extraction of rosmarinic acid from plant matrix |
| title_fullStr | Synthesis, characterization and application of spherical and uniform molecularly imprinted polymeric nanobeads as efficient sorbent for selective extraction of rosmarinic acid from plant matrix |
| title_full_unstemmed | Synthesis, characterization and application of spherical and uniform molecularly imprinted polymeric nanobeads as efficient sorbent for selective extraction of rosmarinic acid from plant matrix |
| title_short | Synthesis, characterization and application of spherical and uniform molecularly imprinted polymeric nanobeads as efficient sorbent for selective extraction of rosmarinic acid from plant matrix |
| title_sort | synthesis characterization and application of spherical and uniform molecularly imprinted polymeric nanobeads as efficient sorbent for selective extraction of rosmarinic acid from plant matrix |
| topic | High-performance liquid chromatography Molecularly imprinted polymeric nanobeads Rosmarinic acid Salvia officinalis Ultrasonic |
| url | http://www.sciencedirect.com/science/article/pii/S2238785421003653 |
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