The role of loneliness in the development of depressive symptoms among partnered dementia caregivers: Evidence from the English Longitudinal Study of Aging

Abstract Background Depressive symptoms are highly prevalent among partnered dementia caregivers, but the mechanisms are unclear. This study examined the mediating role of loneliness in the association between dementia and other types of care on subsequent depressive symptoms. Methods Prospectiv...

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Main Authors: J. P. Saadi, E. Carr, M. Fleischmann, E. Murray, J. Head, A. Steptoe, R. A. Hackett, B. Xue, D. Cadar
Format: Article
Language:English
Published: Cambridge University Press 2021-01-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S0924933821000201/type/journal_article
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author J. P. Saadi
E. Carr
M. Fleischmann
E. Murray
J. Head
A. Steptoe
R. A. Hackett
B. Xue
D. Cadar
author_facet J. P. Saadi
E. Carr
M. Fleischmann
E. Murray
J. Head
A. Steptoe
R. A. Hackett
B. Xue
D. Cadar
author_sort J. P. Saadi
collection DOAJ
description Abstract Background Depressive symptoms are highly prevalent among partnered dementia caregivers, but the mechanisms are unclear. This study examined the mediating role of loneliness in the association between dementia and other types of care on subsequent depressive symptoms. Methods Prospective data from partnered caregivers were drawn from the English Longitudinal Study of Aging. The sample consisted of 4,672 partnered adults aged 50–70 living in England and Wales, followed up between 2006–2007 and 2014–2015. Caregiving was assessed across waves 3 (2006–2007), 4 (2008–2009), and 5 (2010–2011), loneliness at wave 6 (2012–2013), and subsequent depressive symptoms at wave 7 (2014–15). Multivariable logistic regression models were used to assess the association between caregiving for dementia and depressive symptoms compared to caregiving for other illnesses (e.g., diabetes, coronary heart disease (CHD), cancer, and stroke). Binary mediation analysis was used to estimate the indirect effects of caregiving on depressive symptoms via loneliness. Results Care for a partner with dementia was associated with higher odds of depressive symptoms at follow-up compared to those not caring for a partner at all (odds ratio [OR] = 2.6, 95% confidence intervals [CI]: 1.4, 5.1). This association was partially mediated by loneliness (34%). Care for a partner with other conditions was also associated with higher odds of depressive symptoms compared to non-caregiving partners (OR = 1.7, 95% CI: 1.2, 2.5), but there was no evidence of an indirect pathway via loneliness. Conclusion Loneliness represents an important contributor to the relationship between dementia caregiving and subsequent depressive symptoms; therefore, interventions to reduce loneliness among partnered dementia caregivers should be considered.
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spelling doaj.art-72b5a864c2694f9c9585df85a4388ba02023-03-09T12:33:54ZengCambridge University PressEuropean Psychiatry0924-93381778-35852021-01-016410.1192/j.eurpsy.2021.20The role of loneliness in the development of depressive symptoms among partnered dementia caregivers: Evidence from the English Longitudinal Study of AgingJ. P. Saadi0https://orcid.org/0000-0002-4047-031XE. Carr1https://orcid.org/0000-0002-1146-4922M. Fleischmann2https://orcid.org/0000-0001-9023-5150E. Murray3https://orcid.org/0000-0001-6297-6920J. Head4A. Steptoe5https://orcid.org/0000-0001-7808-4943R. A. Hackett6B. Xue7https://orcid.org/0000-0003-0180-8776D. Cadar8https://orcid.org/0000-0003-1398-5841Department of Behavioural Science and Health, University College London, London, United KingdomDepartment of Epidemiology and Public Health, University College London, London, United Kingdom Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United KingdomFaculty of Science, Methodology and Applied Biostatistics, University of Amsterdam, Amsterdam, The NetherlandsDepartment of Epidemiology and Public Health, University College London, London, United KingdomDepartment of Epidemiology and Public Health, University College London, London, United KingdomDepartment of Behavioural Science and Health, University College London, London, United Kingdom Department of Epidemiology and Public Health, University College London, London, United KingdomDepartment of Behavioural Science and Health, University College London, London, United Kingdom Department of Psychology, King’s College London, London, United KingdomDepartment of Epidemiology and Public Health, University College London, London, United KingdomDepartment of Behavioural Science and Health, University College London, London, United Kingdom Abstract Background Depressive symptoms are highly prevalent among partnered dementia caregivers, but the mechanisms are unclear. This study examined the mediating role of loneliness in the association between dementia and other types of care on subsequent depressive symptoms. Methods Prospective data from partnered caregivers were drawn from the English Longitudinal Study of Aging. The sample consisted of 4,672 partnered adults aged 50–70 living in England and Wales, followed up between 2006–2007 and 2014–2015. Caregiving was assessed across waves 3 (2006–2007), 4 (2008–2009), and 5 (2010–2011), loneliness at wave 6 (2012–2013), and subsequent depressive symptoms at wave 7 (2014–15). Multivariable logistic regression models were used to assess the association between caregiving for dementia and depressive symptoms compared to caregiving for other illnesses (e.g., diabetes, coronary heart disease (CHD), cancer, and stroke). Binary mediation analysis was used to estimate the indirect effects of caregiving on depressive symptoms via loneliness. Results Care for a partner with dementia was associated with higher odds of depressive symptoms at follow-up compared to those not caring for a partner at all (odds ratio [OR] = 2.6, 95% confidence intervals [CI]: 1.4, 5.1). This association was partially mediated by loneliness (34%). Care for a partner with other conditions was also associated with higher odds of depressive symptoms compared to non-caregiving partners (OR = 1.7, 95% CI: 1.2, 2.5), but there was no evidence of an indirect pathway via loneliness. Conclusion Loneliness represents an important contributor to the relationship between dementia caregiving and subsequent depressive symptoms; therefore, interventions to reduce loneliness among partnered dementia caregivers should be considered. https://www.cambridge.org/core/product/identifier/S0924933821000201/type/journal_articleDementia caredepressiondepressive symptomsloneliness
spellingShingle J. P. Saadi
E. Carr
M. Fleischmann
E. Murray
J. Head
A. Steptoe
R. A. Hackett
B. Xue
D. Cadar
The role of loneliness in the development of depressive symptoms among partnered dementia caregivers: Evidence from the English Longitudinal Study of Aging
European Psychiatry
Dementia care
depression
depressive symptoms
loneliness
title The role of loneliness in the development of depressive symptoms among partnered dementia caregivers: Evidence from the English Longitudinal Study of Aging
title_full The role of loneliness in the development of depressive symptoms among partnered dementia caregivers: Evidence from the English Longitudinal Study of Aging
title_fullStr The role of loneliness in the development of depressive symptoms among partnered dementia caregivers: Evidence from the English Longitudinal Study of Aging
title_full_unstemmed The role of loneliness in the development of depressive symptoms among partnered dementia caregivers: Evidence from the English Longitudinal Study of Aging
title_short The role of loneliness in the development of depressive symptoms among partnered dementia caregivers: Evidence from the English Longitudinal Study of Aging
title_sort role of loneliness in the development of depressive symptoms among partnered dementia caregivers evidence from the english longitudinal study of aging
topic Dementia care
depression
depressive symptoms
loneliness
url https://www.cambridge.org/core/product/identifier/S0924933821000201/type/journal_article
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